Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma [PDF]
Case Reports in Pathology, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Dana Balitzer +2 more
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The transcription factor CUX1 exerts opposing roles in human and mouse adipocyte differentiation [PDF]
Molecular MetabolismObjective: Adipocyte differentiation is critical for the metabolically protective expansion of adipose tissue. Impaired differentiation drives lipodystrophy and pathologic tissue remodeling, major contributors to cardiometabolic diseases.
Yang Chen +5 more
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Targeting adipocyte differentiation with CRT0066101: activation of AMPK signaling in 3T3-L1 cells [PDF]
Frontiers in PharmacologyIntroductionObesity is characterized by excessive fat accumulation resulting from adipocyte hypertrophy and hyperplasia, with adipocyte differentiation being a central process driving these changes.MethodsThe anti-adipogenic effects of CRT0066101 (CRT ...
Jinque Luo +15 more
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Involvement of long non-coding RNA (lncRNA) MALAT1 in shear stress regulated adipocyte differentiation [PDF]
Frontiers in Bioengineering and BiotechnologyAdipocyte differentiation plays an important role in bone remodeling due to secretory factors that can directly modulate osteoblast and osteoclast, thus affecting overall bone mass and skeletal integrity.
Justin Caron +6 more
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Regulation of Adipocyte Differentiation via MicroRNAs [PDF]
Endocrinology and Metabolism, 2014 Adipocyte differentiation, termed adipogenesis, is a complicated process in which pluripotent mesenchymal stem cells differentiate into mature adipocytes. The process of adipocyte differentiation is tightly regulated by a number of transcription factors,
You Hwa Son +3 more
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Coactosin-like F-actin binding protein (Cotl1) plays a key role in adipocyte differentiation and obesity [PDF]
Communications BiologyActin dynamics, mediated by various actin-binding proteins, plays an important role in adipocyte differentiation. We investigated the role of coactosin-like F-actin binding protein (Cotl1) in adipocyte differentiation in vitro and in vivo.
Eunkuk Park +6 more
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Effects of Flavanone Derivatives on Adipocyte Differentiation and Lipid Accumulation in 3T3-L1 Cells [PDF]
LifeFlavanones, a class of flavonoids, are abundant in fruits, vegetables, and herbs. They are known to have several biological activities, such as anti-inflammatory and anti-cancer activities, but their effects on obesity remain unclear.
Yasuhito Nobushi +10 more
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MYOD1 inhibits avian adipocyte differentiation via miRNA-206/KLF4 axis
Journal of Animal Science and Biotechnology, 2021 Background A considerable number of muscle development-related genes were differentially expressed in the early stage of avian adipocyte differentiation. However, the functions of them in adipocyte differentiation remain largely known. In this study, the
Zheng Wang +7 more
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Immature adipocyte‐derived exosomes inhibit expression of muscle differentiation markers
FEBS Open Bio, 2021 Exosomes are released from a variety of cells to communicate with recipient cells. Exosomes contain microRNAs (miRNAs), which are noncoding RNAs that suppress target genes.
Koichi Ojima +6 more
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Cell Death and Disease, 2022 Obesity is a risk factor for many chronic diseases, and is associated with increased incidence rate of type 2 diabetes, hypertension, dyslipidemia and cardiovascular diseases.
Shuang Kan +14 more
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