Results 31 to 40 of about 946,668 (293)

Thyroid Hormone and Adipocyte Differentiation [PDF]

Thyroid, 2008
Thyroid hormones act as pleiotropic factors in many tissues during development, by regulating genes involved in differentiation. The adipose tissue, a target of thyroid hormones, is the main place for energy storage and acts as a regulator of energy balance, sending signals to keep metabolic control.
openaire   +3 more sources

Regucalcin enhances adipocyte differentiation and attenuates inflammation in 3T3‐L1 cells

FEBS Open Bio, 2020
Dysregulation of adipocyte differentiation and dysfunction play key roles in the pathogenesis of obesity and associated disorders such as diabetes and metabolic syndrome, and as such, a better understanding of the molecular mechanism of adipogenesis may ...
Tomiyasu Murata, Masayoshi Yamaguchi, Susumu Kohno, Chiaki Takahashi, Watanabe Risa, Kanna Hatori, Kiyomi Hikita, Norio Kaneda   +7 more
doaj   +1 more source

Chaperone-mediated autophagy regulates adipocyte differentiation

, 2022
Adipogenesis is a tightly orchestrated multistep process wherein preadipocytes differentiate into adipocytes. The most studied aspect of adipogenesis is its transcriptional regulation through timely expression and silencing of a vast number of genes ...
McCabe, Mericka, Gavathiotis, Evripidis, Lindenau, Kristen, Santiago-Fernández, Olaya, Macho González, Adrián, Dong, Suxhian, Kaushik, Susmita, Dong, Shuxian, Juste, Yves, Singh, Rajat, Macho-González, Adrián, Gavathiotis, Evris, Juste, Yves R., Cuervo, Ana Maria   +13 more
core   +1 more source

Differential Iron Requirements for Osteoblast and Adipocyte Differentiation

JBMR Plus, 2021
ABSTRACT Bone marrow mesenchymal progenitor cells are precursors for various cell types including osteoblasts, adipocytes, and chondrocytes. The external environment and signals act to direct the pathway of differentiation. Importantly, situations such as aging and chronic kidney disease display alterations in the
Daniel F. Edwards, Christopher J. Miller, Arelis Quintana‐Martinez, Christian S. Wright, Matthew Prideaux, Gerald J. Atkins, William R. Thompson, Erica L. Clinkenbeard   +7 more
openaire   +4 more sources

A Pea (Pisum sativum L.) Seed Vicilins Hydrolysate Exhibits PPARγ Ligand Activity and Modulates Adipocyte Differentiation in a 3T3-L1 Cell Culture Model

Foods, 2020
Legume consumption has been reported to induce beneficial effects on obesity-associated metabolic disorders, but the underlying mechanisms have not been fully clarified.
Raquel Ruiz, Raquel Olías, Alfonso Clemente, Luis A. Rubio   +3 more
doaj   +1 more source

Global mapping of cell type-specific open chromatin by FAIRE-seq reveals the regulatory role of the NFI family in adipocyte differentiation. [PDF]

PLoS Genetics, 2011
Identification of regulatory elements within the genome is crucial for understanding the mechanisms that govern cell type-specific gene expression.
Hironori Waki, Masahiro Nakamura, Toshimasa Yamauchi, Ken-ichi Wakabayashi, Jing Yu, Lisa Hirose-Yotsuya, Kazumi Take, Wei Sun, Masato Iwabu, Miki Okada-Iwabu, Takanori Fujita, Tomohisa Aoyama, Shuichi Tsutsumi, Kohjiro Ueki, Tatsuhiko Kodama, Juro Sakai, Hiroyuki Aburatani, Takashi Kadowaki   +17 more
doaj   +1 more source

Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation

Cell Death and Disease, 2022
Adipogenesis is a complex cascade involved with the preadipocytes differentiation towards mature adipocytes, accelerating the onset of obesity. Histone methyltransferase SET and MYND domain-containing protein 2 (Smyd2), is involved in a variety of ...
Haibi Su, Chen Meng, Jie Xu, Zhenghua Su, Chenxi Xiao, Di Yang   +5 more
doaj   +1 more source

Dual-specificity phosphatase 10 controls brown adipocyte differentiation by modulating the phosphorylation of p38 mitogen-activated protein kinase. [PDF]

PLoS ONE, 2013
BackgroundBrown adipocytes play an important role in regulating the balance of energy, and as such, there is a strong correlation between obesity and the amount of brown adipose tissue.
Hye-Ryung Choi, Won Kon Kim, Eun Young Kim, Baek Soo Han, Jeong-Ki Min, Seung-Wook Chi, Sung Goo Park, Kwang-Hee Bae, Sang Chul Lee   +8 more
doaj   +1 more source

Hexane Extract of Chloranthus japonicus Increases Adipocyte Differentiation by Acting on Wnt/β-Catenin Signaling Pathway

Life, 2021
Chloranthus japonicus has been heavily investigated for the treatment of various diseases. This paper attempts to show that Chloranthus japonicus can modulate adipocyte differentiation of preadipocytes.
Ui Jeong Yun, Chu Won Nho, Kye Won Park, Dong Kwon Yang   +3 more
doaj   +1 more source

Waves of sumoylation support transcription dynamics during adipocyte differentiation

, 2022
Tight control of gene expression networks required for adipose tissue formation and plasticity is essential for adaptation to energy needs and environmental cues.
Zhao, Xu, Ghasemi, Fatemeh, Chymkowitch, Pierre, Enserink, Jorrit M, Enserink, Jorrit M., Klungland, Arne, Ramos-Alonso, Lucía, Lien, Guro Flor, Hendriks, Ivo A, Nguea P, Aurelie, Hendriks, Ivo A., Jost, Bernard, Le Gras, Stephanie, Nielsen, Michael L, Ye, Tao, Nielsen, Michael L., Zhao, X. (Xu), Ye, T. (Tao), Le Gras, S. (Stéphanie), Stéphanie Le Gras, Bernard Jost, Lucía Ramos-Alonso, Klungland, A. (Arne), Jorrit M Enserink, Ghasemi, F. (Fatemeh), Arne Klungland, Aurélie Nguéa P, Guro Flor Lien, Ramos-Alonso, L. (Lucía), Michael L Nielsen, Xu Zhao, Lien, G. (Guro Flor), Tao Ye, Ivo A Hendriks, Jost, B. (Bernard), Nguéa P, A. (Aurélie), Pierre Chymkowitch, Chymkowitch, P. (Pierre), Fatemeh Ghasemi   +38 more
core   +1 more source