Results 11 to 20 of about 946,668 (293)
E2Fs Regulate Adipocyte Differentiation [PDF]
Developmental Cell, 2002 When preadipocytes reenter the cell cycle, PPAR gamma expression is induced, coincident with an increase in DNA synthesis, suggesting the involvement of the E2F family of cell cycle regulators. We show here that E2F1 induces PPAR gamma transcription during clonal expansion, whereas E2F4 represses PPARg amma expression during terminal adipocyte ...
Fajas, Lluis +5 more
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Understanding Adipocyte Differentiation
Physiological Reviews, 1998 Gregoire, Francine M., Cynthia M. Smas, and Hei Sook Sul. Understanding Adipocyte Differentiation. Physiol. Rev. 78: 783–809, 1998. — The adipocyte plays a critical role in energy balance. Adipose tissue growth involves an increase in adipocyte size and the formation of new adipocytes from precursor cells.
F M, Gregoire, C M, Smas, H S, Sul
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Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma [PDF]
Case Reports in Pathology, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Dana Balitzer +2 more
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ADIPOCYTE DIFFERENTIATION AND LEPTIN EXPRESSION
Annual Review of Cell and Developmental Biology, 1997 ▪ Abstract Adipose tissue has long been known to house the largest energy reserves in the animal body. Recent research indicates that in addition to this role, the adipocyte functions as a global regulator of energy metabolism. Adipose tissue is exquisitely sensitive to a variety of endocrine and paracrine signals, e.g.
Hwang, C S +3 more
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PLoS ONE, 2020 Adipocytes are derived from pluripotent mesenchymal stem cells through adipogenesis. Pre-adipocyte differentiation in poultry greatly influences fat deposition and meat quality.
Laidi Wang +8 more
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Transcription, adipocyte differentiation, and obesity
Journal of Molecular Medicine, 1996 Differentiation of adipogenic precursor cells into mature adipocytes is a complex phenomenon, characterized by an ordered expression of adipocyte-specific genes, triggered by a set of interacting transcription factors. The most important transcription factors involved in this process are the gamma form of peroxisome proliferator activated receptors ...
J, Auwerx +3 more
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Cellular Physiology and Biochemistry, 2018 Background/Aims: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that acts as soluble modulators of Wnt signaling. Given the substantial rise in obesity, depot-specific fat accumulation and its associated diseases like diabetes,
Hua Guan +7 more
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Effects of Parabens on Adipocyte Differentiation [PDF]
Toxicological Sciences, 2012 Parabens are a group of alkyl esters of p-hydroxybenzoic acid that include methylparaben, ethylparaben, propylparaben, butylparaben, and benzylparaben. Paraben esters and their salts are widely used as preservatives in cosmetics, toiletries, food, and pharmaceuticals.
Pan, Hu +7 more
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Frontiers in Molecular Biosciences, 2020 BackgroundObesity is characterized by increased adipose tissue mass that results from increased fat cell size (hypertrophy) and number (hyperplasia). The molecular mechanisms that govern the regulation and differentiation of adipocytes play a critical ...
Wuping Sun +7 more
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The effect of dehydroleucodine in adipocyte differentiation [PDF]
European Journal of Pharmacology, 2011 Dehydroleucodine (DhL) is a sesquiterpene lactone of the guaianolide group with gastric cytoprotective activity. Recent studies have also demonstrated that DhL inhibits the proliferation of vascular smooth muscle cells. In this study we examined the effect of DhL in the differentiation of 3T3-L1 preadipocytes.
Adriana, Galvis +7 more
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