Results 51 to 60 of about 946,668 (293)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Communications BiologyActin dynamics, mediated by various actin-binding proteins, plays an important role in adipocyte differentiation. We investigated the role of coactosin-like F-actin binding protein (Cotl1) in adipocyte differentiation in vitro and in vivo.
Eunkuk Park +6 more
doaj +1 more source
RETRACTED: Calreticulin inhibits commitment to adipocyte differentiation [PDF]
The Journal of Cell Biology, 2008 Calreticulin, an endoplasmic reticulum (ER) resident protein, affects many critical cellular functions, including protein folding and calcium homeostasis. Using embryonic stem cells and 3T3-L1 preadipocytes, we show that calreticulin modulates adipogenesis.
Szabo, Eva +4 more
openaire +3 more sources
Zfp521 is novel modulator of adipocyte commitment and differentiation.
, 2013 Many transcription factors are induced during adipocyte differentiation. Some of these, like members of the AP-1 family, are induced early during adipocyte development. Other transcription factors like PPARγ promote adipocyte differentiation.
Jacqueline M. Stephens (297020)
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Effects of Flavanone Derivatives on Adipocyte Differentiation and Lipid Accumulation in 3T3-L1 Cells
LifeFlavanones, a class of flavonoids, are abundant in fruits, vegetables, and herbs. They are known to have several biological activities, such as anti-inflammatory and anti-cancer activities, but their effects on obesity remain unclear.
Yasuhito Nobushi +10 more
doaj +1 more source
SINO Syndrome Causative KIDINS220/ARMS Gene Regulates Adipocyte Differentiation
Frontiers in Cell and Developmental Biology, 2021 Nonsense variants in KIDINS220/ARMS were identified as the main cause of spastic paraplegia, intellectual disability, nystagmus, and obesity (SINO) syndrome, a rare disease with birth defects in brachycephaly, neurological disorder, and obesity.
Kaihui Zhang +22 more
doaj +1 more source
Porcine adipocyte differentiation model.
, 2013 During the process of differentiation, (A) lipid droplets gradually accumulated, (B) TG concentration increased dramatically on day 2 and day 8, measured as described in Materials and Methods.
Yongliang Zhang (122202) +8 more
core +1 more source
Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration
Advanced Healthcare Materials, EarlyView.This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu +4 more
wiley +1 more source
KD025 (SLx-2119) suppresses adipogenesis at intermediate stage in human adipose-derived stem cells
Adipocyte, 2019 Rho-associated kinases (ROCKs) have been reported to antagonize adipocyte differentiation, and inhibition of ROCKs by small molecules promotes adipogenesis.
Duy Trong Vien Diep +4 more
doaj +1 more source