Results 221 to 230 of about 348,557 (287)

Nutritional priorities to support GLP‐1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society

Obesity, EarlyView.
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian, Monica Agarwal, Monica Aggarwal, Lydia Alexander, Caroline M. Apovian, Shagun Bindlish, Jonathan Bonnet, W. Scott Butsch, Sandra Christensen, Eugenia Gianos, Mahima Gulati, Alka Gupta, Debbie Horn, Ryan M. Kane, Jasdeep Saluja, Deepa Sannidhi, Fatima Cody Stanford, Emily A. Callahan   +17 more
wiley   +1 more source

Plasma Endocannabinoids Are Independently Associated With the Metabolic Function of White Adipose Tissue.

J Clin Endocrinol Metab
Dion D, Noll C, Fortin M, Haroune L, Saibi S, Sarret P, Carpentier AC.   +6 more
europepmc   +1 more source

Brd9 antagonism induces beige adipocytes in white adipose tissues and protects against diet-induced obesity. [PDF]

Obesity (Silver Spring)
Liu Y, Yin A, Seese K, Fu W, Yin H.
europepmc   +1 more source

Impact of Postoperative Weight Changes on Hypoglossal Nerve Stimulation Success for Obstructive Sleep Apnea

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Obesity is a well‐established risk factor for obstructive sleep apnea (OSA), and weight loss is often recommended alongside hypoglossal nerve stimulation (HGNS) in continuous positive airway pressure‐intolerant patients. Our study assesses how long‐term changes in body mass index (BMI) following HGNS impact surgical success.
Chihun J. Han, Praneet C. Kaki, Jennifer A. Goldfarb, Thomas M. Kaffenberger, Nicole L. Molin, Anna Matzke, Maurits S. Boon, Colin T. Huntley   +7 more
wiley   +1 more source

Chronic BPAF exposure differentially enhances fat deposition in mice fed normal or high-fat diets via lipid metabolism dysregulation. [PDF]

Front Endocrinol (Lausanne)
Lv Z, Xu X, Tang Z, Liang Y, Peng C, Wu Y, Sang D, Jia G, Hu X, Chen Y, Liu G, Wang D, Huang S, Guo Y.   +13 more
europepmc   +1 more source

Precision Medicine in Oncology: Imatinib Dosing in the Obese Cancer Population Using Virtual Clinical Trials

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT This study investigates the impact of obesity on imatinib pharmacokinetics in cancer patients by utilizing physiologically based pharmacokinetic modeling (PBPK) and virtual clinical trial approaches and evaluates the effectiveness of therapeutic drug monitoring (TDM)–guided dose adjustment to recover the imatinib trough concentration (Cmin ...
Khairulanwar Burhanuddin, Afzal Mohammed, Nurul Afiqah Burhanuddin, Raj K. S. Badhan   +3 more
wiley   +1 more source

Combination of Berberine and Evodiamine Alleviates Obesity by Promoting Browning in 3T3-L1 Cells and High-Fat Diet-Induced Mice. [PDF]

Int J Mol Sci
Zhang H, Xiong P, Zheng T, Hu Y, Guo P, Shen T, Zhou X.   +6 more
europepmc   +1 more source

Fusogenic Nanoreactor‐Based Detection of Extracellular Vesicle‐derived miRNAs for Diagnosing Atherosclerosis

Small, EarlyView.
This study introduces an all‐in‐one diagnostic system that amplifies target genes through interactions between serum EVs and fusogenic liposomes. Using padlock probes and enzymes within liposomes, the system enables miRNA amplification upon fusion. It successfully detects miR‐33a, miR‐126, and miR‐145, showing strong diagnostic performance comparable ...
Jiyoon Lee, Kiyoon Kwon, Min Ji Cho, Taesang Son, Yuna Roh, Sugi Lee, Dae‐Soo Kim, Moo‐Seung Lee, Hyun Seung Ban, Jang‐Seong Kim, Eun‐Kyung Lim, Sang‐Hak Lee, Goo Taeg Oh, Jong‐Gil Park, Tae‐Su Han   +14 more
wiley   +1 more source

Epitranscriptomic Role of m6A in Obesity-Associated Disorders and Cancer Metabolic Reprogramming. [PDF]

Genes (Basel)
Yan S, Wen W, Mo Z, Gu S, Chen Z.
europepmc   +1 more source