Results 231 to 240 of about 348,557 (287)

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo‐Epidermal Skin Substitutes

Small Methods, EarlyView.
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche, Monica Nanni, Phil Cheng, Nicolà Caflisch, Aizhan Tastanova, Céline Jenni, Mitchell P. Levesque, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann   +9 more
wiley   +1 more source

Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu, Rongchang Li, Jing Nie, Jinshen He, Zihao Lin, Xiaomin Wu, Jinyu Tan, Zishan Liu, Longyuan Zhou, Xiaozhi Li, Zhirong Zeng, Minhu Chen, Shixian Hu, Yijun Zhu, Ren Mao   +14 more
wiley   +1 more source

Beyond body mass index: exploring the role of visceral adipose tissue in intensive care unit outcomes. [PDF]

BJA Open
Ralston MR, McCreath G, Lees ZJ, Salt IP, Sim MAB, Watson MJ, Freeman DJ.   +6 more
europepmc   +1 more source

Key Predictors of Relevant Weight Loss in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims Weight loss is an effective therapeutic strategy for patients with metabolic dysfunction‐associated steatotic liver disease (MASLD). This study aimed to identify factors that predict relevant weight loss, defined as at least 7% of initial body weight, in MASLD outpatients.
Nicola Pugliese, Ivan Arcari, Federica Cerini, Rosa Lombardi, Federica Turati, Grazia Pennisi, Matteo Soleri, Simone Rocchetto, Diletta De Deo, Michele Sagasta, Chiara Masetti, Anna Ludovica Fracanzani, Salvatore Petta, Carlo La Vecchia, Mauro Viganò, Alessio Aghemo   +15 more
wiley   +1 more source

CT and MRI Key Features of Benign Tumors and Tumor-like Lesions of the Tongue: A Pictorial Review. [PDF]

Cancers (Basel)
Pietragalla M, Gattuso E, Nardi C, Lo Casto A.   +3 more
europepmc   +1 more source

Obesity Alters the Vascular Morphology and VEGF‐A Signaling in Adipose Tissue

FASEB BioAdvances, EarlyView.
Obesity alters cell geometry and vessel morphology in mice adipose tissue by increasing adipocyte size by 78% and reducing vessel density by 51%, while vessel size and capillary basement membrane thickness remain unchanged. Obesity also affects angiogenesis, which is mediated by vascular endothelial growth factor (VEGF) binding kinetics.
Yunjeong Lee, Keith Lionel Tukei, Yingye Fang, Shobhan Kuila, Xinming Liu, Princess I. Imoukhuede   +5 more
wiley   +1 more source

Exploring the Science of Shape: How Physical Activity, Sleep, and Stress Affect Body Composition. [PDF]

Healthcare (Basel)
Maruszczak K, Kasperek W, Kustra K, Baran J, Kochman M.   +4 more
europepmc   +1 more source

Different action of glucocorticoid receptor in adipose tissue remodelling to modulate energy homeostasis by chronic restraint stress. [PDF]

Lipids Health Dis
Luo Y, Liu Q, Mao Y, Wen J, Chen G.
europepmc   +1 more source

The Impact of Toll‐Like Receptor 5 on Liver Function in Age‐Related Metabolic Disorders

Aging Cell, EarlyView.
Toll‐like receptor 5 (TLR5) deficiency accelerates age‐related metabolic disorders, leading to obesity, fatty liver, and cellular changes such as lipid accumulation in PMHs (hepatocytes) and activation of HSCs (hepatic stellate cells), which drive fibrosis.
Dong‐Hyun Kim, Hye Sun Go, Eun Jae Jeon, Thi Quynh Trang Nguyen, Da Yeon Kim, Hansung Park, Hyo‐Ji Eom, Sung Young Kim, Sang Chul Park, Kyung A Cho   +9 more
wiley   +1 more source

Exploration of Conserved Human Adipose Subpopulations Using Targeted Single-Nuclei RNA Sequencing Data Sets. [PDF]

J Am Heart Assoc
Potts CM, Yang X, Lynes MD, Malka K, Liaw L.   +4 more
europepmc   +1 more source