Results 261 to 270 of about 496,074 (351)

Significance of neuroendocrine systems and the gut-brain axis (GBA) in the regulation of obesity. [PDF]

PeerJ
Zhao H, Li Y, Cheng R, Wang Y, Ma L, Chen W.   +5 more
europepmc   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

Antibiotic-Mediated Modulation of the Gut Microbiome Identifies Taurine as a Modulator of Adipocyte Function Through TGR5 Signaling. [PDF]

Int J Mol Sci
Jäger E, Peeva V, Gnad T, Haange SB, Rolle-Kampczyk U, Stäubert C, Krumbholz P, Heiker JT, Gebhardt C, Krügel U, Sen P, Harazin M, Stab V, Münzker J, Hamdani N, Pfeifer A, von Bergen M, Till A, Fenske WK.   +18 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Editorial: Dietary influences on white and brown adipose tissue: mechanisms and health implications. [PDF]

Front Nutr
Reymond Simoes M, Bombassaro B, Monfort-Pires M.   +2 more
europepmc   +1 more source

Salivary microbiota and clinical periodontal measures predicting cardiometabolic disease mortality: A nationwide survey

Journal of Periodontology, EarlyView.
Abstract Background Although periodontitis and oral microbiota are linked to cardiometabolic diseases (CMD), it is unclear if they similarly predict CMD mortality. We compared the predictive ability of salivary microbiota and periodontal disease measures for CMD mortality in the National Health and Nutrition Examination Survey (NHANES).
Hamdi S. Adam, Weihua Guan, Abigail J. Johnson, Sanaz Sedaghat, Charlene Goh, James S. Pankow, Ryan T. Demmer   +6 more
wiley   +1 more source

Immunometabolism in obesity: Understanding the beneficial and detrimental roles of inflammation. [PDF]

PLoS Biol
Lee YS.
europepmc   +1 more source

Liver stiffness in patients with Shwachman‐Diamond syndrome

JPGN Reports, EarlyView.
Abstract Objective This case series aims to describe whether transient elastography (TE) as a marker of liver stiffness is associated with clinically important liver disease in children and young adults with Shwachman‐Diamond Syndrome (SDS). Methods All patients ≤25 years of age with genetically confirmed SDS seen in the Pediatric Gastroenterology ...
Sabina Sabharwal, Amit Grover, Paul Mitchell, Jessica Serino‐Cipoletta, Akiko Shimamura, Rima Fawaz   +5 more
wiley   +1 more source

Cancer-Associated Cachexia in the Era of Obesity. [PDF]

Int J Mol Sci
de Resende JCF, Andrade MF, Ferreira FA, Otoch JP, Motta-Teixeira LC, Seelaender M.   +5 more
europepmc   +1 more source

Comparative effects of superheated steam and hot air roasting on the in vitro phospholipase A2 inhibitory activity and polyphenol composition of cocoa beans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Cocoa, derived from Theobroma cacao, is a popular food ingredient used to produce chocolate. Cocoa is rich in polyphenols and human and laboratory model studies have indicated that cocoa and chocolate can mitigate chronic inflammatory conditions.
Sawali Navare, Bethany H. Lam, Misha T. Kwasniewski, Ramaswamy Anantheswaran, Joshua D. Lambert   +4 more
wiley   +1 more source