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White adipose tissue and cardiovascular disease

Best Practice & Research Clinical Endocrinology & Metabolism, 2005
Adipocytes have recently been shown to secrete a variety of bioactive substances called 'adipocytokines', and have been recognized as endocrine cells. Tumour necrosis factor (TNF)-alphaalpha, plasminogen activator inhibitor-1 (PAI-1) and heparin-binding epidermal-growth-factor-like growth factor (HBEGF) are among these adipocytokines, and they ...
openaire   +3 more sources

Sandwiched White Adipose Tissue: A Microphysiological System of Primary Human Adipose Tissue

Tissue Engineering Part C: Methods, 2018
White adipose tissue (WAT) is a critical organ in both health and disease. However, physiologically faithful tissue culture models of primary human WAT remain limited, at best. In this study we describe a novel WAT culture system in which primary human WAT is sandwiched between tissue-engineered sheets of adipose-derived stromal cells.
Maxwell Hunt   +12 more
openaire   +3 more sources

Cellular senescence and its role in white adipose tissue

International Journal of Obesity, 2021
U. Smith   +3 more
semanticscholar   +1 more source

In Vitro Culture of White Adipose Tissue

White adipose tissue (WAT) plays a crucial endocrine organ that regulates blood glucose and lipid levels, satiety, and inflammation. Before the described technique, primary white adipocytes could not be stably cultured in vitro. The lack of a reliable primary culture model impeded research in WAT metabolism and drug development.
Jake J, Fontenot, Frank H, Lau
openaire   +2 more sources

White Adipose Tissue as an Endocrine Organ

2009
The survival of free fat used as an autograft is operator dependent and requires delicate handling of the graft tissue, careful washing of the fat to minimize extraneous blood cells, and installation into a site with adequate vascularity. There is evidence that fat cells will survive and that filling of defects is not from the residual collagen ...
openaire   +2 more sources

The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue

Reviews in Endocrine & Metabolic Disorders, 2019
J. Moreno-Navarrete, J. Fernández-Real
semanticscholar   +1 more source

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