Results 271 to 280 of about 492,704 (351)

WDR4-mediate tRNA m7G modification to promote mitophagy and browning of white adipose tissue for ameliorating obesity in male mice. [PDF]

Adipocyte
Lin B, Wang C, Yang Y, Liu Z, Mu P, Xu W, Li Y.   +6 more
europepmc   +1 more source

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

Journal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt, Nathalie Struwe, Annika Jansson, Vesna Munic Kos, Maria Larsson, Jana M. Weiss   +5 more
wiley   +1 more source

A Mouse Model of Lipoatrophy Reveals Relationships Between Beige Fat Appearance and Female Fertility.

Endocrinology
Anaya ES, Dion W, Saha PK, Cox AR, de Groot E, Ahmed AA, Felix JB, Zhu B, Pangas SA, Hartig SM.   +9 more
europepmc   +1 more source

The Monocrotaline Model of Hypertension Leads to Cachexia in Male but Not Female Mice. [PDF]

J Cachexia Sarcopenia Muscle
Politeski AL, Rico AQL, Cambell J, Cisneros Medrano JG, Witmer B, Gupta R, Fiorucci NA, Lycett KM, Smith HC, Kavanagh HM, Robertson CE, Brenner IKM, Shafer ABA, Bates HE, Hillsley K, Tobin SW.   +15 more
europepmc   +1 more source

Six Hundred and Sixty Nanometer Light Exposure‐Induced Alterations in Actin Filament, Mitochondrial Morphological Dynamics, and Migration in Mesenchymal Stem Cells

Journal of Biophotonics, EarlyView.
Six hundred and sixty nanometer light‐induced alteration of actin filament cytoskeleton, mitochondrial morphological dynamics, and enhanced migration in adipose‐derived mesenchymal stem cells. ABSTRACT Actin cytoskeleton alteration and cell homing/migration are crucial determinants for the success of stem cell (SC) based therapy.
Mahima Rastogi, Khageswar Sahu, Shovan Kumar Majumder   +2 more
wiley   +1 more source

White and brown adipose tissue share a convergent fibro-adipogenic progenitor population. [PDF]

EMBO Rep
Bui HV, Hansen JK, Lo Sardo V, Galmozzi A.   +3 more
europepmc   +1 more source

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Pharmacological inhibition of Ubiquitin-Specific Peptidase 10 (USP10) with spautin-1 attenuates adipogenesis through CCAAT/Enhancer-Binding Protein Beta (C/EBPβ) destabilization. [PDF]

Mol Biomed
Erdenebileg Z, Simamora DD, Park JK, Nogueira R, Kim YB, Choi JY, Kang HG, Choi HS, Baek JH, Chun KH.   +9 more
europepmc   +1 more source

Salivary microbiota and clinical periodontal measures predicting cardiometabolic disease mortality: A nationwide survey

Journal of Periodontology, EarlyView.
Abstract Background Although periodontitis and oral microbiota are linked to cardiometabolic diseases (CMD), it is unclear if they similarly predict CMD mortality. We compared the predictive ability of salivary microbiota and periodontal disease measures for CMD mortality in the National Health and Nutrition Examination Survey (NHANES).
Hamdi S. Adam, Weihua Guan, Abigail J. Johnson, Sanaz Sedaghat, Charlene Goh, James S. Pankow, Ryan T. Demmer   +6 more
wiley   +1 more source

Obese plasma transfer accelerates cellular aging in the C57BL/6 mouse model. [PDF]

Immun Ageing
Shahabi Nejad S, Zand H, Rastgoo S, Bahreini Boroujeni LZ, Abedini Najafabadi M, Asadi S, Hamishe Bahar R, Shimi G.   +7 more
europepmc   +1 more source