Results 71 to 80 of about 493,971 (354)

Adipose tissue: colors, depots and functions

Ожирение и метаболизм, 2021
Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
doaj   +1 more source

Characterization of breast tissues in density and effective atomic number basis via spectral X-ray computed tomography [PDF]

, 2023
Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in terms of tissue density and effective atomic number by exploiting the energy dependence of $\mu$. In this work, 5
arxiv   +1 more source

Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue

Diabetes, 2017
Adipose-derived stem cells (ADSCs) play critical roles in controlling obesity-associated inflammation and metabolic disorders. Exosomes from ADSCs exert protective effects in several diseases, but their roles in obesity and related pathological ...
Hui Zhao, Qianwen Shang, Zhenzhen Pan, Yang Bai, Zequn Li, Huiying Zhang, Qiu Zhang, Chun Guo, Lining Zhang, Qun Wang   +9 more
semanticscholar   +1 more source

Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice [PDF]

, 2021
Chronic systemic low-level inflammation in metabolic disease is known to affect adipose tissue biology. Lysozyme (LYZ) is a major innate immune protein but its role in adipose tissue has not been investigated.
Becerril, Sara, Comas, Ferran, Fernández-Real, José Manuel, Frühbeck, Gema, Gavaldà i Navarro, Aleix, Giralt i Oms, Marta, Latorre, Jèssica, Lluch, Aina, Moreno-Navarrete, José M., Morón-Ros, Samantha, Ortega, Francisco J., Ricart, Wifredo, Rodríguez, Amaia, Villarroya i Gombau, Francesc   +13 more
core   +1 more source

The Chemerin Receptor CMKLR1 Requires Full‐Length Chemerin for High Affinity in Contrast to GPR1 as Demonstrated by a New Nanoluciferase‐Based Binding Assay

ChemMedChem, Volume 17, Issue 23, December 5, 2022., 2022
The adipokine chemerin and the short peptide agonist chemerin‐9 activate two GPCRs: CMKLR1 and GPR1. Here, we established a nanoluciferase based binding assay to analyze differences in ligand binding. For GPR1, both ligands show high affinity and comparable binding.
Anne Sophie Czerniak, Kevin Kretschmer, Tina Weiß, Annette G. Beck‐Sickinger   +3 more
wiley   +1 more source

Cold-induced lipid dynamics and transcriptional programs in white adipose tissue

BMC Biology, 2019
In mammals, cold exposure induces browning of white adipose tissue (WAT) and alters WAT gene expression and lipid metabolism to boost adaptive thermogenesis and maintain body temperature.
Ziye Xu, Wenjing You, Yanbing Zhou, Wentao Chen, Yizhen Wang, T. Shan   +5 more
semanticscholar   +1 more source

Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling [PDF]

, 2015
BACKGROUND: Large mammals are capable of thermoregulation shortly after birth due to the presence of brown adipose tissue (BAT). The majority of BAT disappears after birth and is replaced by white adipose tissue (WAT).
Basse, Astrid L., Dixen, Karen, Gupta, Ramneek, Hansen, Jacob B., Kristiansen, Karsten, Quistorff, Bjorn, Qvortrup, Klaus, Tygesen, Malin P., Wang, Jun, Yadav, Rachita   +9 more
core   +3 more sources

White adipose tissue as a target for cadmium toxicity

Frontiers in Pharmacology, 2022
Cadmium (Cd) is a widespread heavy metal known as a toxic environmental pollutant. Cd exposure is threatening due to its bioaccumulation trait in living systems that exceeds 35 years without a beneficial biological role. Acute exposure to high Cd doses was reported to impact adipose tissue (AT) function adversely.
Sarra Mohammed Attia, Sarra Mohammed Attia, Sandra Concepcion Das, Sandra Concepcion Das, Kavitha Varadharajan, Hamda A. Al-Naemi, Hamda A. Al-Naemi   +6 more
openaire   +3 more sources

Maternal obesity and resistance to breast cancer treatments among offspring: Link to gut dysbiosis

Cancer Reports, Volume 5, Issue 12, December 2022., 2022
Abstract Background About 50 000 new cases of cancer in the United States are attributed to obesity. The adverse effects of obesity on breast cancer may be most profound when affecting the early development; that is, in the womb of a pregnant obese mother.
Fabia de Oliveira Andrade, Vivek Verma, Leena Hilakivi‐Clarke   +2 more
wiley   +1 more source

FatSegNet : A Fully Automated Deep Learning Pipeline for Adipose Tissue Segmentation on Abdominal Dixon MRI [PDF]

, 2019
Purpose: Development of a fast and fully automated deep learning pipeline (FatSegNet) to accurately identify, segment, and quantify abdominal adipose tissue on Dixon MRI from the Rhineland Study - a large prospective population-based study. Method: FatSegNet is composed of three stages: (i) consistent localization of the abdominal region using two 2D ...
arxiv   +1 more source