Results 161 to 170 of about 609,118 (384)
Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis
Advanced Science, EarlyView.Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao +15 more
wiley +1 more source
Adipose tissue and inflammation [PDF]
International Journal of Clinical Practice, 2011 McGinty, Ann, Young, Ian
openaire +5 more sources
Hypolipidemic effect of brown seaweed (Sargassum crassifolium) extract in vivo (Study of histopathology, mRNA expression, and immunohistochemistry (IHC) with VCAM-1, ICAM-1, and MCP-1 parameters) [PDF]
arXivThe purpose of this study was to obtain natural drugs from brown seaweed (Sargassum crassifolium) as antiatherosclerosis candidates through the study of hypolipidemic mechanisms of action. Modeling of dyslipidemia rats was carried out by feeding high-fat (HFF) and doses of crude fucoidan 100. 200. 400mg / KgBB.
arxiv
Advanced Science, EarlyView.This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng +8 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang +13 more
wiley +1 more source
Clinical overview on RASopathies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022 Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
EXPERIMENTAL FAT NECROSIS: THE ACTION OF PANCREATIC TISSUE UPON SUBCUTANEOUS ADIPOSE TISSUE [PDF]
, 1898 HERBERT U. WILLIAMS
openalex +1 more source
Advanced Science, EarlyView.This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu +11 more
wiley +1 more source
Characteristics and mechanisms of subcutaneous and visceral adipose tissue aging
Chinese Journal of Plastic and Reconstructive SurgeryAging is one of the most significant health challenges worldwide and is a primary cause of chronic diseases and physiological decline. Among the myriad changes that occur with aging, alterations in adipose tissue distribution and function have gained ...
Peng Xu, Yikai Wang, Kai Liu
doaj
Adipoparacrinology: an Emerging Field in Biomedical Research
Balkan Medical Journal, 2012 White adipose tissue (WAT) is a dynamic multicellular assembly composed of adipocytes and stromovascular cells, including fibroblasts, endothelial and immune cells, nerve fibers, and stem cells. In humans, WAT is a responsive and secretory (endocrine and
George N. Chaldakov +11 more
doaj