A Heparin‐Functionalized Scaffold with HB‐EGF Immobilization for Tissue Engineering
Advanced Healthcare Materials, EarlyView.In this study, a heparin‐functionalized scaffold is designed for bio‐mimicking growth factors reservoir function of extracellular matrix. Due to the presence of heparin‐binding domain, heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is effectively and spatially captured by heparin‐functionalized scaffold.
Bowu Peng +8 more
wiley +1 more source
Sparse multi-view matrix factorisation: a multivariate approach to multiple tissue comparisons
, 2015 Gene expression levels in a population vary extensively across tissues. Such heterogeneity is caused by genetic variability and environmental factors, and is expected to be linked to disease development. The abundance of experimental data now enables the
Montana, Giovanni, Wang, Zi, Yuan, Wei
core +1 more source
Obesity is associated with macrophage accumulation in adipose tissue.
Journal of Clinical Investigation, 2003 S. Weisberg +5 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.A translational spray‐coating strategy that conformationally activates fibronectin and collagen via mechanical unfolding is presented. Microscale droplets enable uniform extracellular matrix (ECM) depositions on biomedical substrates and wound closure enhancement.
Albertus Ivan Brilian +11 more
wiley +1 more source
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
Advanced Healthcare Materials, EarlyView.3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source
THE EFFECT OF LIPOLYTIC HORMONES AND THEOPHYLLINE ON HEAT PRODUCTION IN BROWN ADIPOSE TISSUE IN VIVO [PDF]
, 1967 F. Cockburn, D. Hull, Isobel Walton
openalex +1 more source
Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
Advanced Healthcare Materials, EarlyView.In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley +1 more source
Defect in Glucose Utilization in Adipose Tissue of Patients with Maturity-onset Diabetes [PDF]
, 1969 D. J. Galton, J. P. D. Wilson
openalex +1 more source
Obesity induces a phenotypic switch in adipose tissue macrophage polarization.
Journal of Clinical Investigation, 2007 C. Lumeng, Jennifer L Bodzin, A. Saltiel
semanticscholar +1 more source
Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk
Advanced Healthcare Materials, EarlyView.Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor +12 more
wiley +1 more source