Results 171 to 180 of about 4,454,068 (344)
Advanced Science, EarlyView.METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang +8 more
wiley +1 more source
Advanced Science, EarlyView.These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang +9 more
wiley +1 more source
Inactivation and Protection of Fructose Diphosphate Aldolase in Rat Adipose Tissue Extracts
, 1969 Lea Reshef, Michael J. Heller
openalex +1 more source
THE EFFECT OF LIPOLYTIC HORMONES AND THEOPHYLLINE ON HEAT PRODUCTION IN BROWN ADIPOSE TISSUE IN VIVO [PDF]
, 1967 F. Cockburn, D. Hull, Isobel Walton
openalex +1 more source
Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand
Advanced Science, EarlyView.Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li +16 more
wiley +1 more source
Clearing-factor lipase in adipose tissue. A medium in which the enzyme activity of tissue from starved rats increases in vitro [PDF]
, 1966 M R Salaman, Robinson Ds
openalex +1 more source
Advanced Science, EarlyView.This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo +10 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen +9 more
wiley +1 more source