Results 181 to 190 of about 4,454,068 (344)
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia+29 more
wiley +1 more source
Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT). [PDF]
Liu D+11 more
europepmc +1 more source
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan+11 more
wiley +1 more source
Do Rats Have Epicardial Adipose Tissue? [PDF]
Kleszczewska M+5 more
europepmc +1 more source
Adipose-tissue pyruvate kinase. Properties and interconversion of two active forms [PDF]
C. I. Pogson
openalex +1 more source
D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing+9 more
wiley +1 more source
Adipose tissue-associated Krt23+fibroblasts contribute to immune microenvironment disorders in mouse adipose tissue during the development of obesity. [PDF]
Lu Z+7 more
europepmc +1 more source
Glycogen and adipose tissue [PDF]
E. Tuerkischer, E. Wertheimer
openaire +3 more sources
Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji+12 more
wiley +1 more source