Results 221 to 230 of about 4,454,348 (409)
Clearing-factor lipase in adipose tissue. Distinction of different states of the enzyme and the possible role of the fat cell in the maintenance of tissue activity [PDF]
Vincent J. Cunningham, D. S. Robinson
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Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang+16 more
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Adipose tissue and androgens: the ins and outs. [PDF]
Jia Y, Lacombe M, Muller C, Milhas D.
europepmc +1 more source
KRAS mutations dynamically remodel the tumor microenvironment (TME), fostering immunosuppression, metabolic symbiosis, and stromal plasticity. This review dissects how oncogenic KRAS variants sculpt TME networks and explores actionable vulnerabilities. Emerging strategies combining KRAS inhibitors and TME‐editing approaches offer potential to dismantle
Jiayao Ma+9 more
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Regulation of glycolysis and
Mitchell L. Halperin, R M Denton
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The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang+8 more
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cTAGE5 is essential for adipogenesis and adipose tissue development. [PDF]
Fan J+12 more
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Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang+10 more
wiley +1 more source