Results 221 to 230 of about 4,280,291 (335)

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

Cytosolic Versus Lysosomal Lipolysis in Adipose Tissue: Opposing Roles in Cardiometabolic Disease. [PDF]

Arterioscler Thromb Vasc Biol
Yeh YS, Huang J, Liu Z, Cosme C, Zhang X, Razani B.   +5 more
europepmc   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet-Induced Adipose Tissue Inflammation. [PDF]

J Endocr Soc
Hope MC, Unger CA, Kettering MC, Socia CE, Aladhami AK, Rice BC, Niamira DS, Wiznitzer BP, Altomare D, Cotham WE, Enos RT.   +10 more
europepmc   +1 more source

Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types

Nature Metabolism, 2019
Jinchu Vijay, Marie-Frédérique Gauthier, R. Biswell, Daniel A. Louiselle, J. Johnston, W. Cheung, Bradley Belden, A. Pramatarova, L. Biertho, M. Gibson, Marie-Michelle Simon, H. Djambazian, A. Staffa, G. Bourque, A. Laitinen, J. Nystedt, M. Vohl, J. Fraser, T. Pastinen, A. Tchernof, E. Grundberg   +20 more
semanticscholar   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

Advanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao, Yajie Peng, Hongyan Lei, Tianyi Wang, Huajuan Wang, Bo Wang, Jin Li, Xiaoying Li, Xuelian Xiong   +8 more
wiley   +1 more source

Proinflammatory polarization of adipose tissue macrophages in cows with subclinical ketosis constitutes a critical driver of adipose tissue remodeling and inflammation. [PDF]

J Anim Sci Biotechnol
Zhao B, Li M, Zhang H, Chang R, Wang J, Zhao W, Yang Y, Usman M, Loor JJ, Xu C.   +9 more
europepmc   +1 more source

Impaired expression of mitochondrial and adipogenic genes in adipose tissue from a patient with acquired partial lipodystrophy (Barraquer-Simons syndrome): a case report [PDF]

, 2008
Jordi P Guallar, Ricardo Rojas‐García, Elena García‐Arumí, Joan Carles Domingo, Eduard Gallardo, Antoni L. Andreu, Peré Domingo, Isabel Illa, Marta Giralt, Francesc Villarroya   +9 more
openalex   +1 more source

Adipose Tissue [PDF]

International Journal of Obesity, 2001
openaire   +1 more source

Abdominal Visceral and Subcutaneous Adipose Tissue Compartments: Association With Metabolic Risk Factors in the Framingham Heart Study

Circulation, 2007
Caroline S Fox, Joseph M. Massaro, U. Hoffmann, Karla M. Pou, P. Maurovich-Horvát, Chunyu Liu, R. Vasan, J. Murabito, J. Meigs, L. Cupples, Ralph B. D’Agostino, Christopher J. O’Donnell   +11 more
semanticscholar   +1 more source