Results 261 to 270 of about 4,454,348 (409)

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Combining small extracellular vesicles with decellularized adipose tissue hydrogel for the construction of tissue-engineered adipose

Materials & Design
Soft tissue defects from trauma or surgery remain challenging to repair due to poor regenerative capacity and fibrosis. Adipose tissue-derived small extracellular vesicles (sEVs) have emerged as promising agents for promoting adipogenesis and driving ...
Pengyu Hong, Shengmeng Yuan, Jian Yang, Zhiwei Cao, Xiangyun Sun, Ling Du, Dianri Wang, Jian Pan   +7 more
doaj  

SF3A3 Drives Tumorigenesis in Endometrial Cancer by Enhancing c‐FOS Expression and Represents a Potential Therapeutic Target

Advanced Science, EarlyView.
The role of splicing factor 3A subunit 3 (SF3A3) in driving endometrial cancer (EC) progression and potential therapeutic interventions. SF3A3, a core component of the U2 small nuclear ribonucleoprotein (U2 snRNP), is upregulated in endometrial cancer (EC) and promotes tumor growth and cisplatin resistance. RNA‐binding protein immunoprecipitation (RIP)
Wei Yu, Yi Gu, Hengrui Zhang, Wunan Huang, Lei Sun, Liangjian Ma, Xiaolei Liang, Lexin Liu, Guiping Chen, Weihua Wang, Zhongkai Cao, Xue Li, Xiangjun Chen, Lidan Hu   +13 more
wiley   +1 more source

Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue. [PDF]

Chin Med
Huang Z, Zhao Z, Shi H, He R, Feng Q, Geng Y, Zhang L, Zhang T, Yan Z, Jia Z, Jiang Y, Sun J, Cai A, Dong S, Yang L.   +14 more
europepmc   +1 more source

Control of the Metabolism and Lipolytic Effects of Cyclic 3′,5′-Adenosine Monophosphate in Adipose Tissue by Insulin, Methyl Xanthines, and Nicotinic Acid

, 1968
Melvin Blecher, Nancie S. Merlino, J T Ro'Ane   +2 more
openalex   +1 more source

Accumulation of succinate controls activation of adipose tissue thermogenesis

Nature, 2018
E. Mills, K. Pierce, Mark P. Jedrychowski, Ryan Garrity, Sally Winther, S. Vidoni, T. Yoneshiro, J. Spinelli, Gina Z. Lu, L. Kazak, Alexander S. Banks, M. Haigis, S. Kajimura, M. Murphy, S. Gygi, C. Clish, Edward T. Chouchani   +16 more
semanticscholar   +1 more source

Adipose Tissue in Evolution

, 2014
openaire   +3 more sources

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Cysteine depletion triggers adipose tissue thermogenesis and weight loss. [PDF]

Nat Metab
Lee AH, Orliaguet L, Youm YH, Maeda R, Dlugos T, Lei Y, Coman D, Shchukina I, Andhey PS, Smith SR, Ravussin E, Stadler K, Chen B, Artyomov MN, Hyder F, Horvath TL, Schneeberger M, Sugiura Y, Dixit VD.   +18 more
europepmc   +1 more source

Toxic effects of a chlorothiazide-diazoxide combination on adipose tissue and kidneys of intact rats [PDF]

, 1968
Harold Settle, William J. Munsie, John Owen   +2 more
openalex   +1 more source