Results 281 to 290 of about 4,454,348 (409)

ER‐phagy Activation by AMFR Attenuates Cardiac Fibrosis Post‐Myocardial Infarction via mTORC1 Pathway

open access: yesAdvanced Science, EarlyView.
By catalyzing FAM134B ubiquitination and activating ER‐phagy, AMFR alleviates progressive fibrosis and cardiac dysfunction by inhibiting the mTORC1 pathway. Consequently, these findings underscore the essential role of AMFR‐driven ER‐phagy in mitigating the progression of fibrotic responses, offering a potential therapeutic target for preventing heart ...
Zhixiang Wang   +10 more
wiley   +1 more source

GDF15 links adipose tissue lipolysis with anxiety. [PDF]

open access: yesNat Metab
Townsend LK   +24 more
europepmc   +1 more source

Respiratory Processes in Brown Adipose Tissue

open access: hybrid, 1968
M S Kornacker, Eric G. Ball
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

open access: yesAdvanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen   +6 more
wiley   +1 more source

Metabolic adaptation and maladaptation in adipose tissue

open access: yesNature Metabolism, 2019
Edward T. Chouchani, S. Kajimura
semanticscholar   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Large‐Scale Bioprinting of Human Epiblast‐Like Models Featuring Disc‐Shaped Morphogenesis and Gastrulation Events

open access: yesAdvanced Science, EarlyView.
Large‐scale generation of disc‐shaped models mimicking human epiblast layer is achieved by bioprinting of human pluripotent stem cells using a well‐defined biomatrix. The bioactive component and physical confinement from laminin/alginate microgels, combined with the endogenous regulation of the WNT signaling pathway regulated disc‐like morphogenesis ...
Yixue Luo   +11 more
wiley   +1 more source

Adipose tissue-derived PRXL2A suppresses hepatic lipogenesis in a study with male mice. [PDF]

open access: yesNat Commun
Li Z   +8 more
europepmc   +1 more source

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