Results 281 to 290 of about 4,418,865 (434)

Perivascular adipose tissue dysfunction contributes to thoracic aortic aneurysm development. [PDF]

open access: yesCardiovasc Diabetol
Wang Z   +12 more
europepmc   +1 more source

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

open access: yesAdvanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang   +16 more
wiley   +1 more source

CeiTEA: Adaptive Hierarchy of Single Cells with Topological Entropy

open access: yesAdvanced Science, EarlyView.
CeiTEA, a novel hierarchical clustering algorithm based on topological entropy, effectively captures complex structures underlying data. By constructing an adaptive multi‐nary partition tree, CeiTEA reveals hierarchical structures and local diversifications, outperforming existing methods in clustering accuracy and consistency and providing the ...
Bowen Tan   +3 more
wiley   +1 more source

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

open access: yesAdvanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu   +13 more
wiley   +1 more source

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction. [PDF]

open access: yesMol Nutr Food Res
Martins FF   +6 more
europepmc   +1 more source

Accumulation of succinate controls activation of adipose tissue thermogenesis

open access: yesNature, 2018
E. Mills   +16 more
semanticscholar   +1 more source

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