Results 291 to 300 of about 4,418,865 (434)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Adipose Tissue in Evolution

, 2014
openaire   +3 more sources

The citrate cleavage pathway and lipogenesis in rat adipose tissue: replenishment of oxaloacetate

, 1967
F J Ballard, Richard W. Hanson
openalex   +1 more source

Tβ4‐Engineered ADSC Extracellular Vesicles Rescue Cell Senescence Through Separable Microneedle Patches for Diabetic Wound Healing

Advanced Science, EarlyView.
A separable microneedle patch is designed for Tβ4–modified ADSC‐derived extracellular vesicles delivery. The overexpressed Tβ4 released from the microneedles can mitigate cellular senescence and promote wound healing via the PTEN/PI3K/AKT pathway, offering a promising approach for diabetic wound treatment. This bioengineered therapeutic system serve as
Youjun Ding, Jinglin Wang, Jiaye Li, Yi Cheng, Shuyin Zhou, Yepeng Zhang, Yuanjin Zhao, Min Zhou   +7 more
wiley   +1 more source

Rat adipose tissue lipases: hormone-sensitive lipase activity against triglycerides compared with activity against lower glycerides

, 1964
Ove Strand, Martha Vaughan, Daniel Steinberg   +2 more
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

MTCH2 Suppresses Thermogenesis by Regulating Autophagy in Adipose Tissue. [PDF]

Adv Sci (Weinh)
Zhao XY, Zhao BC, Li HL, Liu Y, Wang B, Li AQ, Zeng TS, Hui HX, Sun J, Cikes D, Gheldof N, Hager J, Mi JX, Laybutt DR, Deng YY, Shi YC, Neely GG, Wang QP.   +17 more
europepmc   +1 more source

Fatty Acid Synthesis in Human Adipose Tissue

, 1969
E. Shrago, Terry Spennetta, Ellen R. Gordon   +2 more
openalex   +1 more source

Single-cell analysis of human adipose tissue identifies depot- and disease-specific cell types

Nature Metabolism, 2019
Jinchu Vijay, Marie-Frédérique Gauthier, R. Biswell, Daniel A. Louiselle, J. Johnston, W. Cheung, Bradley Belden, A. Pramatarova, L. Biertho, M. Gibson, Marie-Michelle Simon, H. Djambazian, A. Staffa, G. Bourque, A. Laitinen, J. Nystedt, M. Vohl, J. Fraser, T. Pastinen, A. Tchernof, E. Grundberg   +20 more
semanticscholar   +1 more source

Frontiers in Nondrug Treatment of Sarcopenia: A Review of Pathological Mechanisms and the Latest Treatment Strategies

AGING MEDICINE, EarlyView.
This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang, Yu‐Qing Ni, You‐Shuo Liu   +2 more
wiley   +1 more source