Results 341 to 350 of about 4,507,088 (388)

Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

Advanced Science, EarlyView.
Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun, Qili Qian, Luwen Xu, Bowen Gao, Ting Li, Yin Li, Jiayi Zheng, Qiaoyu Fu, Xi Cheng, Nuo Chen, Sijia Wang, Liang Zhang, Caiyue Liu, Qingfeng Li   +13 more
wiley   +1 more source

Early adipose tissue wasting in a preclinical model of human lung cancer cachexia. [PDF]

Cell Rep
Snoke DB, van der Velden JL, Bellafleur ER, Dearborn JS, Lenahan SM, Beal AE, Aboushousha R, Heininger SCJ, Ather JL, Mank MM, Sarausky H, Stephenson D, Reisz JA, D'Alessandro A, Majumdar D, Ahern TP, Xu K, Sandler KL, Landman BA, Janssen-Heininger YMW, Poynter ME, Seward DJ, Toth MJ.   +22 more
europepmc   +1 more source

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

Bioengineered Skin Grafts from Patient‐Derived Decellularized Extracellular Matrix and Autologous Cells for Personalized Regenerative

Advanced Science, EarlyView.
This study presents a patient‐specific skin model using autologous cells, decellularized dermal ECM, and keratin–alginate bioinks. The model supports cell compatibility, collagen deposition, and epidermal differentiation within a biomimetic ECM environment.
RaeHui Kang, Suyeon Shin, Yurim Choi, WonJun Jang, Soojin Park, Mi Kyung Lee, Hyun‐Jong Cho, Yu Shrike Zhang, Han‐Jun Kim, Bo Young Park, Junmin Lee   +10 more
wiley   +1 more source

Adipose Tissue, at the Core of the Action of Incretin and Glucagon-Based Anti-Obesity Drugs. [PDF]

Curr Obes Rep
Villarroya F, Peyrou M, Giralt M.
europepmc   +1 more source

Intramuscular adipose tissue restricts functional muscle recovery. [PDF]

Cell Rep
Norris AM, Palzkill VR, Appu AB, Fierman KE, Noble CD, Ryan TE, Kopinke D.   +6 more
europepmc   +1 more source

Obesity Alters the Vascular Morphology and VEGF-A Signaling in Adipose Tissue. [PDF]

FASEB Bioadv
Lee Y, Tukei KL, Fang Y, Kuila S, Liu X, Imoukhuede PI.   +5 more
europepmc   +1 more source

Genetic regulation of fatty acid content in adipose tissue

Yan X, Roberts AL, El-Sayed Moustafa JS, Villicaña S, Al-Hilal M, Tomlinson M, Menni C, Sanders TAB, Freidin MB, Bell JT, Small KS.   +10 more
europepmc   +1 more source

Rapidly decellularized adipose tissue induces soft tissue vascularization in potential anatomical spaces. [PDF]

BMC Biotechnol
Marcin P, Alicja H, Paweł M, Elwira L, Krzysztof M, Mirosław J, Piotr W, Justyna D.   +7 more
europepmc   +1 more source

Radiation Promotes Acute and Chronic Damage to Adipose Tissue. [PDF]

Int J Mol Sci
Liermann-Wooldrik KT, Kosmacek EA, McDowell JA, Takkar S, Murthy D, Singh PK, Schott MB, Ponnusamy MP, Oberley-Deegan RE.   +8 more
europepmc   +1 more source