Results 191 to 200 of about 220,180 (319)

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

PTPN2 targets TAK1 for dephosphorylation to improve cellular senescence and promote adipose tissue browning in T2DM. [PDF]

Front Pharmacol, 2023
Liu Y, Han L, Zhu P, Song M, Zhang Y, Meng L, Zhang W, Zhang C, Zhong M.   +8 more
europepmc   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Nano-Encapsulated Berberine Is a Potential Therapeutic Agent for Adipose Tissue Browning in C57BL/6J Mice. [PDF]

Medicina (Kaunas)
Alpaslan A, Uçar Baş K, Örs Demet ED, Tuğal Aslan D, Reçber T, Öztürk SC, Gulsun T, Çelebier M, Göktaş Z.   +8 more
europepmc   +1 more source

Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis. [PDF]

Sci Rep, 2023
Deschemin JC, Ransy C, Bouillaud F, Chung S, Galy B, Peyssonnaux C, Vaulont S.   +6 more
europepmc   +1 more source

Gut Microbiota Interacts with Markers of Adipose Tissue Browning, Insulin Action and Plasma Acetate in Morbid Obesity

Molecular Nutrition & Food Research, 2018
J. Moreno-Navarrete, M. Serino, V. Blasco-Baque, V. Azalbert, R. H. Barton, M. Cardellini, J. Latorre, F. Ortega, Mònica Sabater-Masdeu, R. Burcelin, M. Dumas, W. Ricart, M. Federici, J. Fernández-Real   +13 more
semanticscholar   +1 more source

Comparative effects of superheated steam and hot air roasting on the in vitro phospholipase A2 inhibitory activity and polyphenol composition of cocoa beans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Background Cocoa, derived from Theobroma cacao, is a popular food ingredient used to produce chocolate. Cocoa is rich in polyphenols and human and laboratory model studies have indicated that cocoa and chocolate can mitigate chronic inflammatory conditions.
Sawali Navare, Bethany H. Lam, Misha T. Kwasniewski, Ramaswamy Anantheswaran, Joshua D. Lambert   +4 more
wiley   +1 more source

Enhancing fat graft retention through adipose tissue browning: a systematic review. [PDF]

Stem Cell Res Ther
Qiu H, Wang H, Ji Q, Wu D.
europepmc   +1 more source

Angiotensin II Promotes White Adipose Tissue Browning and Lipolysis in Mice. [PDF]

Oxid Med Cell Longev, 2022
Cai Z, Fang L, Jiang Y, Liang M, Wang J, Shen Y, Wang Z, Liang F, Huo H, Pan C, Shen L, He B.   +11 more
europepmc   +1 more source

Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment.

ACS Nano, 2017
Yuqi Zhang, Qiongming Liu, Jicheng Yu, Shuangjiang Yu, Jinqiang Wang, L. Qiang, Zhen Gu   +6 more
semanticscholar   +1 more source