Results 181 to 190 of about 14,567 (295)

Angiotensin II Promotes White Adipose Tissue Browning and Lipolysis in Mice. [PDF]

open access: yesOxid Med Cell Longev, 2022
Cai Z   +11 more
europepmc   +1 more source

Obesity and pony breed are associated with plasma L‐lactate in horses with acute gastrointestinal disease

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Plasma L‐lactate (lactate) is widely used as a prognostic marker in horses with acute gastrointestinal disease (colic), but association with obesity is unclear. In humans, plasma lactate is correlated with obesity and insulin resistance. Objectives This study aims to evaluate the association of obesity (body condition score ≥7/9) and
A. L. Tillisch   +4 more
wiley   +1 more source

Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge

open access: yesEquine Veterinary Education, EarlyView.
Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David   +4 more
wiley   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

open access: yesThe FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova   +12 more
wiley   +1 more source

Regulation of redox homeostasis by ATF4-MTHFD2 axis during white adipose tissue browning. [PDF]

open access: yesRedox Biol
Ginting RP   +8 more
europepmc   +1 more source

Maternal secretin ameliorates obesity by promoting white adipose tissue browning in offspring. [PDF]

open access: yesEMBO Rep, 2022
Xue L   +21 more
europepmc   +1 more source

ADAM17 and its proteolytic targets in disease pathogenesis

open access: yesThe FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

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