Results 91 to 100 of about 268,511 (302)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Pseudo-Dolly-In Video Generation Combining 3D Modeling and Image Reconstruction [PDF]
Published in: 2017 IEEE International Symposium on Mixed and Augmented Reality (ISMAR-Adjunct) Date of Conference: 9-13 Oct.
KAMEDA Yoshinari +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
The influence of substituting barley malt with milled rice on the sensory and chemical characteristics of nonalcoholic beers (NAB) was investigated. Physicochemical and volatile analyses were conducted on the NABs.
Christian Schubert +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Implication sémantique des prédicats dans la grammaire à base sémantique de Stanisław Karolak
The following paper discusses the problem of the semantic implication of predicates based on Stanisław Karolak’s theory of semantics-based grammar. As the notion of predicate-argument structure is fundamental for this theory, it is crucial to establish ...
Beata Śmigielska
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Another look at recapitulation [PDF]
As an understanding of the work of Christ, the belief of the very early church father Irenaeus has been tragically neglected. Supported by a couple of biblical references, especially Ephesians 1:10, Irenaeus interpreted the life and death of Jesus as a ...
Prof David T Williams, Adjunct Professor
doaj
The aim of the present study is to explore online practices for teaching English as a Foreign Language (EFL) to adult learners in higher education in Turkey with emphasis on examining online practices implemented to teach English during the Covid-19 ...
Mirici, Ismail Hakki, Gümüş, Özge
core +1 more source

