Results 171 to 180 of about 554,925 (310)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
A commentary on "High prevalence of metabolic comorbidities in Asian children with type 1 diabetes and obesity". [PDF]
Ann Pediatr Endocrinol MetabLim HH.
europepmc +1 more source
Seeking the Path to Adjunct Justice at Marquette University [PDF]
, 2008 Maguire, Daniel C.
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Methylprednisolone as an adjunct to intravenous immunoglobulin in pediatric Guillain-Barré syndrome: a prospective comparative study. [PDF]
Sci RepFayed AI, Elsayeh AA, Hassan MAS.
europepmc +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Advanced therapy in familial hypercholesterolemia. [PDF]
Can Fam PhysicianGao E, Brunham LR, Goldman RD.
europepmc +1 more source