Results 71 to 80 of about 554,925 (310)

МОДЕЛЬ СПІВПРАЦІ НАУКОВОГО КЕРІВНИКА ТА АСПІРАНТА В ПРОЦЕСІ НАУКОВО-ПЕДАГОГІЧНОГО СУПРОВОДУ ЗА МЕТОДИКОЮ ПРОФЕСІЙНОГО РОЗВИТКУ

open access: yesSučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015
У статті автором обґрунтовано модель співпраці наукового керівника та аспіранта в процесі науково-педагогічного супроводу у системи вищої військової освіти.
Igor M. Kozubtsov
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The role of intellectual property rights on access to medicines in the WHO African region: 25 years after the TRIPS agreement

open access: yesBMC Public Health, 2021
Background It is now 25 years since the adoption of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) and the same concerns raised during its negotiations such as high prices of medicines, market exclusivity and delayed ...
Marion Motari   +6 more
doaj   +1 more source

Textual Function in the Jakarta Post Editorials [PDF]

open access: yes, 2014
This research deals with Theme and Rheme in Editorials texts of The Jakarta Post newspaper. The aims are to find out the optional element dominates the structure of theme in the editorials of The Jakarta Post newspaper and to describe where the optional ...
Naibaho, N. S. (Novita)   +1 more
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Argument-Adjunct Scale: Applied Nominal and Locative Phrases in Xhosa

open access: yesLinguistic Discovery, 2018
This paper examines the categorial status of applied elements in Xhosa with respect to their argumenthood or adjuncthood. By analyzing the response of nominal and locative applied elements to various criteria and diagnostics and by adopting the ...
Alexander Andrason
doaj   +1 more source

Operational Galois Adjunctions [PDF]

open access: yes, 2000
24 pages - survey with proofs; Chapter of the volume: 'Current Research in Operational Quantum Logic: Algebras, Categories, Languages', Fundamental Theories of Physics 111, Kluwer Academic Publishers (2000); edited by Bob Coecke, David Moore and Alex Wilce pp.
Coecke, Bob, Moore, David
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Unclear Predication in the Construction

open access: yesE-REA, 2012
This paper examines Evaluative Adjectives (in short: EAs) like brave, clever, crazy, foolish, silly, wise when followed by to + infinive as in (1) or (2):(1) C8T 2147 I suppose I'm silly to worry about that.
Christopher DESURMONT
doaj   +1 more source

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