Results 121 to 130 of about 1,585,740 (230)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
COMPARISON OF MARITAL SATISFACTION AND QUALITY OF LIFE IN PEOPLE WITH OBSESSIVE COMPULSIVE DISORDER AND OTHER ANXIETY DISORDERS AND NORMAL PEOPLE [PDF]
Background & Aims : the current study was conducted in the order to compare marital satisfaction and quality of life between patients with obsessive compulsive disorder, patients with other anxiety disorders and normal group.
مولوی, پرویز +2 more
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Psychiatry and Behavioral SciencesObjective: Coping mechanisms are important responses to stress, and although they differ in psychiatric disorders, maladaptive ones are mostly used. This study aimed to compare coping strategies in adolescents diagnosed with anxiety disorder (AD), major ...
Melike Kevser Gul +3 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Taḥqīqāt-i ̒Ulūm-i Raftārī, 2017 Aim and Background: The aim of present study was investigating the efficacy of acceptance and commitment therapy (ACT) for couples on marital adjustment in men with bipolar II Disorder.
مصطفی عرب ورنوسفادرانی +4 more
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Fargo, North Dakota Board of Adjustment Papers 1928-1933 [PDF]
, 2015 The Fargo, North Dakota Board of Adjustment Papers contains the minutes of the Board, 1928-1933. The Board of Adjustment was an administrative agency that served to consider variances and special exceptions to ordinances, and heard appeals of ...
Fargo (N.D.). Board of Adjustment
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