Results 131 to 140 of about 184,354 (240)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Development and validation of the "Adjustment Disorder Scale for Medically Ill Patients - ETAM". [PDF]

Front Psychiatry
Zapata-Ospina JP, Rodríguez N, Rodríguez AM, García-Valencia J, Jiménez-Benítez M, Martínez-Ramos N, Restrepo Bernal D, Gallego AL, Gómez C, Tabares LF, Cardeño-Castro C, Aguirre-Acevedo DC.   +11 more
europepmc   +1 more source

Being a parent, emotional stability, and adjustment disorder symptoms in the face of COVID-19. [PDF]

Fam Relat, 2022
Kestler-Peleg M, Pitcho-Prelorentzos S, Mahat-Shamir M, Kagan M, Lavenda O.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A qualitative contextualisation of childhood adversity, stressors and symptoms of diagnosed adjustment disorder among UK military personnel. [PDF]

Eur J Psychotraumatol
McKenzie A, Burdett H, Greenberg N, Stevelink SAM.   +3 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Investigating COVID-19-Induced Adjustment Disorder Among Iranian Patients With Multiple Sclerosis in Pandemic Time. [PDF]

Neuropsychopharmacol Rep
Samami E, Baghbanian SM, Nezhad SZH, Shahhosseini Z, Moosazadeh M, Elyasi F.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

A Case Study on Post-traumatic Stress Disorder, Prolonged Grief Disorder, and Adjustment Disorder. [PDF]

Cureus
Trivedi GY, Thakore P.
europepmc   +1 more source