Results 241 to 250 of about 69,334 (300)

Recombinant cytokines as immunological adjuvants

Immunology & Cell Biology, 1993
SummaryThis paper describes the bacterial expression and purification of bioactive recombinant ovine interleukin‐2 (rovIL‐2), interleukin‐lα (rovlL‐lα) and tumour necrosis factor α. These purified proteins had specific activities in appropriate bioassays of 1 × 107, 1 times; 107 and 1 × 105 U/mg, respectively.
Nash, AD, Lofthouse, SA, Barcham, GJ, Jacobs, HJ, Ashman, K, Meeusen, Ent, Brandon, MR, Andrews, AE   +7 more
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Immunology of Vaccine Adjuvants

2009
In recent times vaccine adjuvants, or immunopotentiators, received abundant attention in the media as critical ingredients of current and future vaccines. Indeed, vaccine adjuvants are recognized to make the difference between competing vaccines based on identical antigens.
Ribeiro, C.M.S., Schijns, V.E.J.C.
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Immunologic adjuvants

, 2008
Frederick R. Vogel, Stanley L. Hem
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Glucans as Immunological Adjuvants

1995
β-1,3-Linked glucopyranose (β-glucan), a major structural component of yeast, fungi, and algae [1], has a wide range of biological activities. Systemic administration of β-glucan (1) provides nonspecific resistance in experimental animals against a variety of pathogenic challenges [2–7]; (2) prolongs the survival time of tumor-bearing animals [8,9]; (3)
N. Mohagheghpour, M. Dawson, P. Hobbs, A. Judd, R. Winant, L. Dousman, N. Waldeck, L. Hokama, D. Tusé, F. Kos, C. Benike, E. Engleman   +11 more
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Current Status of Immunological Adjuvants

Annual Review of Immunology, 1986
Sixty years ago Ramon demonstrated that it was possible to augment the antitoxin response to diphtheria and tetanus by administering vaccines with pyogenic bacteria or with various additional compounds (1). Since that time, clinicians and immunologists have sought to potentiate the immune response with adjuvants while attempting to minimize the often ...
H S, Warren, F R, Vogel, L A, Chedid
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Glycolipids as potential immunologic adjuvants

Journal of Medicinal Chemistry, 1980
A group of 1-thio-beta-L-fucopyranosides containing hexadecane, 9-octadecene, adamantane, 1,2-diphenyltetrafluoroethane, and 3-hexynyl- and 3,6-dioxaoctylcholesterols were synthesized as potential immunologic adjuvants. Many of these fucosyl lipids and 6-(5-cholesten-3 beta-yloxy)hexyl 1 thioglycosides were found to give good response to subunit A ...
M M, Ponpipom, R L, Bugianesi, T Y, Shen, A, Friedman   +3 more
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L-Tyrosine as an Immunological Adjuvant

International Archives of Allergy and Applied Immunology, 2009
A series of experiments has been carried out to investigate the adjuvant properties of the amino acid L-tyrosine in laboratory animals. Adsorption of various allergenic materials to L-tyrosine was found to enhance the induction of IgG antibodies, but no unusual propensity to stimulate IgE antibody or delayed hypersensitivity was observed ...
A W, Wheeler, D M, Moran, B E, Robins, A, Driscoll   +3 more
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Immunological adjuvants: a role for liposomes

Immunology Today, 1990
Recent technological advances have resulted in the production of safe subunit and synthetic small peptide vaccines. These vaccines are weakly or non-immunogenic and cannot, therefore, be used effectively in the absence of immunological adjuvants (agents that can induce strong immunity to antigens).
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Viruses as immunological adjuvants in cancer

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1974
Abstract Homogenates of tumor cells infected with certain viruses are more immunogenic than similar extracts from noninfected cells. This phenomenon has been most thoroughly studied with nonspecific tumors and influenza virus, but it has also been shown with strain-specific tumors and other viruses.
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Polymerized Micelles and Their Use as Adjuvants in Immunology

Journal of Pharmaceutical Sciences, 1976
A polymerization process is described for the preparation of hydrophilic micelles containing solubilized drug molecules in a colloidal aqueous system of dissolved monomers. A hydrocarbon medium constitutes the outer phase. After secondary solubilization with the aid of selected surfactants, polymerization of micelles under different conditions takes ...
G, Birrenbach, P P, Speiser
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