Results 61 to 70 of about 15,146 (241)
Establishing the pig as a large animal model for vaccine development against human cancer
Frontiers in Genetics, 2015 Immunotherapy has increased overall survival of metastatic cancer patients, and cancer antigens are promising vaccine targets. To fulfill the promise, appropriate tailoring of the vaccine formulations to mount in vivo cytotoxic T cell (CTL) responses ...
Nana Haahr Overgaard +8 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni +11 more
wiley +1 more source
Arquivos Brasileiros de Cardiologia, 2007 Apesar de relativamente recente, nota-se um acúmulo crescente e robusto de evidências experimentais e clínicas que apontam um estado gradativo de ativação imune-inflamatória em pacientes com insuficiência cardíaca (IC).
Angelo Michele de Candia +2 more
doaj +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Ciência Rural, 2002 O Pythium insidiosum é um fungo zoospórico que se desenvolve em locais alagadiços e que pode infectar humanos e animais, principalmente eqüinos. A infecção natural nesta espécie resulta em pitiose clínica, uma doença granulomatosa de difícil tratamento ...
Alexandre Trindade Leal +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
Adverse events of vaccines and the consequences of non-vaccination: a critical review
Revista de Saúde Pública, 2018 OBJECTIVE: To analyze the risks related to vaccines and the impacts of non-vaccination on the world population. METHODS: This is a narrative review that has considered information present in the bibliographic databases NCBI-PubMed, Medline, Lilacs, and ...
Luana Raposo de Melo Moraes Aps +5 more
doaj +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Current status and future prospects for the development of substance abuse vaccines
Expert Review of Vaccines, 2017 Introduction: Substance use disorders (SUD) are a significant threat to both individual and public health. To date, SUD pharmacotherapy has focused primarily on agonist medications (i.e.
R. David Heekin +2 more
doaj +1 more source
PLoS ONE, 2020 Development of a successful HIV vaccine is dependent upon a determination of the optimum antigen and adjuvant as well as choosing an optimal site for vaccine delivery.
Bridget S Fisher +6 more
doaj +1 more source