Antigenic peptides Aβ42 and E7 self‐assemble into nanofibrils; APTES and TEOS induce SiO2 NP formation on these fibrils to form SiO2@fibril nanovaccines, which activate BMDCs in vitro. In vivo, SiO2@Aβ42 fibril nanovaccines alleviate AD symptoms and clear Aβ42 plaques in APP/PS1 mice, and SiO2@E7 fibril nanovaccines inhibit tumor growth and promote ...
Xuecheng Yang +6 more
wiley +1 more source
The Road toward a Trojan Horse Malaria Vaccine: Chemical Augmentation of Live Sporozoites without Affecting Their Viability. [PDF]
Naar CM +7 more
europepmc +1 more source
Furrow tillage resolves the conventional‐vs.‐no‐tillage trade‐off by simultaneously cutting CO2 efflux to 2.0–3.0 g C m−2 d−1 and unlocking high nutrient availability for the rice rhizosphere. This scalable agronomic solution strengthens soil health, enhances plant physiology, reshapes microbial metabolism, and shifts paddy systems toward a net ...
Arnab Majumdar +10 more
wiley +1 more source
Natural polysaccharides as immune adjuvants to overcome immune checkpoint inhibitor resistance: mechanistic insights, clinical evidence, and translational challenges. [PDF]
Li Y, Qian J, Zhou S, Wang C, Cai.
europepmc +1 more source
A Rare Case of Giant Cell tumor of Bone in Distal Tibia. [PDF]
Thakur R +4 more
europepmc +1 more source
Dexmedetomidine versus magnesium sulphate as adjuvants to ropivacaine in ilioinguinal-iliohypogastric nerve block for inguinal hernia repair: A randomised controlled trial. [PDF]
Senapati LK +4 more
europepmc +1 more source
Advancements in nanomaterial-based adjuvants for animal vaccines. [PDF]
Dai L +7 more
europepmc +1 more source
Efficacy of liposome bupivacaine in transversus abdominis plane blocks for postoperative analgesia: a systematic review and meta-analysis. [PDF]
Cao Q, Lin RM, Liu Y, Liu HL.
europepmc +1 more source
Advances in molecular innate immune regulation in the development and therapeutic strategies of allergic rhinitis vaccines. [PDF]
Liu Y +5 more
europepmc +1 more source
Mechanisms of Action of Adjuvants [PDF]
Adjuvants are used in many vaccines, but their mechanisms of action are not fully understood. Studies from the past decade on adjuvant mechanisms are slowly revealing the secrets of adjuvant activity.
George Mutwiri, Lorne A Babiuk
exaly +2 more sources

