Results 71 to 80 of about 94,628 (218)

Stability and computational analyses of selected pesticides in use in the Republic of Serbia [PDF]

Journal of the Serbian Chemical Society
Pesticides commonly used in the Republic of Serbia (tebuconazole, pendimethalin, pyraclostrobin, propiconazole and famoxadone) have high stability, so their potential toxicity to humans needs to be investigated.
Arsić Biljana, Petrović Stefan, Mrmošanin Jelena, Dimitrijević Ivana, Tošić Snežana, Stojanović Gordana, Glišić Sanja, Milićević Jelena   +7 more
doaj   +1 more source

Bionanomedicine: A “Panacea” In Medicine? [PDF]

, 2017
Recent advances in nanotechnology, biotechnology, bioinformatics, and materials science have prompted novel developments in the field of nanomedicine. Enhancements in the theranostics, computational information, and management of diseases/disorders are ...
Anurogo, D. (Dito), Ikrar, T. (Taruna), Parikesit, A. A. (Arli)   +2 more
core   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Geometry Optimization, Molecular Docking and ADMET Studies of Echimidine Molecule

Cumhuriyet Science Journal
Plants are an important food group that has been used as a source of nutrition and healing from past to present. Plants contain secondary metabolites that are still under investigation in drug development studies.
Bilge Bıçak
doaj   +1 more source

Insights into the molecular basis of some chalcone analogues as potential inhibitors of Leishmania donovani: An integrated in silico and in vitro study

Open Chemistry, 2022
Protozoal infections caused by species belonging to Leishmania donovani complex are responsible for the most severe form of leishmaniasis, especially in Sudan and other developing countries.
Osman Marwa S., Awad Talal A., Shantier Shaza W., Garelnabi Elrashied A. E., Mukhtar Moawia M., Osman Wadah, Mothana Ramzi A., Elhag Rashid I.   +7 more
doaj   +1 more source

Radiative Transfer Limits of Two-Frequency Wigner Distribution for Random Parabolic Waves [PDF]

, 2006
The present note establishes the self-averaging, radiative transfer limit for the two-frequency Wigner distribution for classical waves in random media. Depending on the ratio of the wavelength to the correlation length the limiting equation is either a ...
Albert C. Fannjiang, Blomgren, Derode, Derode, Fannjiang, Fannjiang, Fannjiang, Fannjiang, Fannjiang, Ishimaru, Mishchenko, Ryzhik   +11 more
core   +8 more sources

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

ChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda, Sami A. Al‐Hussain, Basant Farag, Mohamed El‐Naggar, Magdi E. A. Zaki, Emad S. A. Alhazmi, Adel S. M. Almohammadi, Sobhi M. Gomha   +7 more
wiley   +1 more source

A New Candidate for the Treatment of Alzheimer's Disease; Synthesis, Characterization, Investigation of Drug Properties with In Silico Methods

Cumhuriyet Science Journal
Brain disorder-caused mortality has emerged as the second of all diseases worldwide in the 21st century. Alzheimer’s Disease (AD) is the most common disease that takes place among brain disorders according to statistics.
Tolga Acar Yeşil, Tahir Tilki, Ömer Dilek   +2 more
doaj   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

In Silico Studies of a Novel Scaffold of Acetylsalicylic Acid Derivatives Against EGFR by Molecular Docking and Molecular Dynamics Simulations

Cumhuriyet Science Journal
In this study, a molecular docking study was performed to propose the acetylsalicylic acid derivative 2-[(4-Acetylphenyl)carbamoyl]phenyl acetate (AMPBS) as a potential cancer candidate targeting the Epidermal Growth Factor Receptor (EGFR).
Alpaslan Bayrakdar
doaj   +1 more source