Results 81 to 90 of about 31,497 (236)

Exploring naringenin-clozapine combination for synergistic antipsychotic action: An in-silico study [PDF]

BIO Web of Conferences
Naringenin has natural origins with reported antioxidant and neuromodulator properties, and clozapine is a prominent atypical antipsychotic with known dopaminergic and serotonergic mechanisms.
Arora Nikita, Gauba Pammi, Dang Shweta
doaj   +1 more source

Hydrophobic Natural Deep Eutectic Solvents for Sustainable CO2 Capture: Molecular Insights From Multiscale Modeling

ChemPhysChem, Volume 27, Issue 18, 28 September 2026.
Multiscale DFT, COSMO‐RS, and molecular dynamics reveal how a biobased piperitone:linoleic acid deep eutectic solvent captures CO2:hydrogen bonding, and apolar domains create nanoscale pockets that selectively adsorb CO2 over N2/O2 at the gas–liquid interface, with efficient thermal desorption enabling sustainable, low‐toxicity carbon‐capture cycles ...
Nuria Aguilar, Sara Rozas, Pedro A. Marcos, Alfredo Bol, Santiago Aparicio   +4 more
wiley   +1 more source

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi-Target Inhibitors of Cholinesterases and Carbonic Anhydrases. [PDF]

J Biochem Mol Toxicol
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Ünlü S, Köksal Z, Kırboğa KK, Tuncel Elmalı F.   +3 more
europepmc   +2 more sources

Microwave-assisted ADMET polymerization

, 2015
Microwave-assisted ADMET polymerization is reported on a series of α,ω-diene monomers, both polar and non-polar. Investigations indicate that of the multiple microwave modes possible, constant power is the most advantageous, providing polymers up to M‾w ...
Rojas Jiménez, Giovanni, Wagener, Kenneth B., Williams, Kathryn R., Gaines, Taylor W.   +3 more
core   +1 more source

Piperazine and Morpholine Protoporphyrin IX Derivatives Intensify Biomolecules Oxidation and Phototoxicity in Triple‐Negative Breast Cancer

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Protoporphyrin IX derivatives bearing piperazine or morpholine substituents exhibit enhanced cellular retention and photodynamic activity in triple‐negative breast cancer cells. Structural modification promotes oxidative stress, alters mitochondrial membrane potential, and increases caspase‐3 activity, providing new structure–activity relationship ...
Maynne Duarte Suriani Franco, Thibault Joseph William Jacques Dit Lapierre, Tarcisio Paiva Mendonça, Luiz Felipe Fernandes Peixoto, Renata Roland Teixeira, Joyce Ferreira Da Costa Guerra, Kelly Aparecida Geraldo Yoneyama Tudini, Daniele Lisboa Ribeiro, Foued Salmen Espindola, Allisson Benetti Justino, Celso de Oliveira Rezende Júnior, Tayana Mazin Tsubone   +11 more
wiley   +1 more source

In silico investigation of the mechanism of ricin-catalysed depurination reaction and design of novel ricin inhibitors [PDF]

, 2012
Includes abstract.Includes bibliographical references.Ricin is a dimeric enzyme found in the castor bean plant. It is extremely toxic with a fatal dose for humans ranging from 0.1-1.0 ug/kg. This has lead to its use as a biological weapon.
Jayakody, Ranga S
core   +1 more source

Thalamita admete

, 2019
Thalamita admete (Herbst, 1803) Material examined. 1 female (15.0 x 10.7 mm) (DABFUK), Kavaratti, 18 January 2015. This species was also observed from Minicoy (R. Ravinesh) but specimens not collected. Remarks. Thalamita admete was also observed from Minicoy but specimens were not collected.
Devi, S. Suvarna, Mendoza, Jose C. E., Ravinesh, R., Idress Babu, K. K., Kumar, A. Biju, Ng, Peter K. L.   +5 more
openaire   +1 more source

Assessment of the Targeted Therapeutic Potential of Naringenin‐Benzyl Piperazine Derivatives on Hypoxia‐Induced JAK/STAT Pathway in Breast and Ovarian Cancers

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
The synthesized naringenin‐benzyl piperazine derivatives 3b, 3f, and 3g exhibited potent antiproliferative and cytotoxic activities on breast tumors (MCF7 (ER‐α+), SK‐Br, MDA‐MB‐231) and ovarian cancer cells (NIH‐OVCAR‐3, and SKOV‐3). 3f was found to have the highest apoptotic effect among the other derivatives.
Hafize Özcan, Oğuzhan Doğanlar, Zeynep Banu Doğanlar, Ayşen Şuekinci Yılmaz, Ömer Zaim   +4 more
wiley   +1 more source

The potential of Mitragyna speciosa leaves as a natural source of antioxidants for disease prevention

Journal of Integrative Bioinformatics
Mitragyna speciosa is famous for its addictive effect. On the other hand, this plant has good potential as an antioxidant agent, and so far, it was not explicitly explained what the most contributing compound in the leaves to that activity is. This study
Arief Ihsanul, Sunnardianto Gagus Ketut, Khairi Syahrul, Saputri Wahyu Dita   +3 more
doaj   +1 more source

Functional Precision Polymers via ADMET Polymerization

, 2015
Acyclic diene metathesis (ADMET) polymerization is a powerful and versatile technique for creating precision polymers. Specialized and well-defined materials, as well as improved understanding of structure–property relationships, can be achieved by ADMET
Bachler, Patricia R., Wagener, Kenneth B.   +1 more
core   +1 more source