Results 161 to 170 of about 117,049 (245)

Twenty‐year survival outcomes after multipeptide vaccination for resected high‐risk melanoma: A post‐hoc analysis of a randomized clinical trial

International Journal of Cancer, EarlyView.
What's New? While melanoma vaccines have shown therapeutic promise, predicting their clinical benefits is challenged by factors such as delayed response to immunotherapy and scarcity of biomarkers. Here, the authors examined the long‐term efficacy of vaccination with either 4 or 12 class I MHC‐restricted peptides in high‐risk melanoma.
Emily K. Ninmer, Hong Zhu, Kimberly A. Chianese‐Bullock, Craig L. Slingluff Jr.   +3 more
wiley   +1 more source

Integrated diagnosis and successful treatment of imported old world cutaneous leishmaniasis with intralesional sodium stibogluconate in china: a case report. [PDF]

Parasitol Res
Xu J, Xia X, Liu Z.
europepmc   +1 more source

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

The First Dorsal Metatarsal Artery Perforator Flap: A Description and Anatomical Study. [PDF]

J Clin Med
Saboye M, Majchrzak A, d'Andréa G, Bronsard N, Camuzard O, Lupon E.   +5 more
europepmc   +1 more source

TBCancer: A database for exploring characteristics and functions of tissue‐biased genes in cancer

iMetaOmics, EarlyView.
This study defined 10,921 tissue‐biased genes across 54 normal tissues and 41 cancer types. Tumor‐associated tissue‐biased genes exhibit downregulation, mutations, and epigenetic modifications, correlating with poor clinical outcomes. Their inactivation promotes tumorigenesis by enhancing stemness and immune evasion, highlighting their value as ...
Zhuobin Lin, Kunhua Hu, Hongyan Sun, Xiaoqiong Bao, Lin Tang, Wei Liu, Zhixiang Zuo, Zhihang Chen   +7 more
wiley   +1 more source

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Afimetoran, a Toll-Like Receptor 7 and 8 Inhibitor, in Patients With Cutaneous Lupus Erythematosus: A Phase 1b Randomized, Double-Blind, Placebo-Controlled Study. [PDF]

ACR Open Rheumatol
Hosein F, Ignatenko S, Chadwick KD, Zhu L, Baribaud F, Saini J, Bach T, Aras U, Zhang W, Karabeber H, Dawes M, Harrison M, Carayannopoulos LN, Krishna G.   +13 more
europepmc   +1 more source

Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations

Interdisciplinary Medicine, EarlyView.
Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang   +12 more
wiley   +1 more source

Challenges in Diagnosing Biopsy-Negative Cutaneous Leishmaniasis and Role of Systemic Therapies. [PDF]

Cureus
Rafique S, Rafique A, Rahu A, Shafi S, Rajper A.   +4 more
europepmc   +1 more source

Diagnosis and management of reactive infectious mucocutaneous eruption

Journal of Hospital Medicine, EarlyView.
Abstract Medicine's clinical understanding of reactive infectious mucocutaneous eruption (RIME) has evolved over time. It was previously described as Mycoplasma pneumoniae‐induced rash and mucositis (MIRM), and before that as a variant of Stevens‐Johnson Syndrome/Toxic Epidermal Necrolysis. Here, we summarize the current understanding of best practices
Nicole Damari, Abbie Goodman, Catherine Bridges   +2 more
wiley   +1 more source

Granulocyte colony-stimulating factor-producing cutaneous squamous cell carcinoma: A case report and literature review. [PDF]

Medicine (Baltimore)
Ishiguro A, Iwashita N, Otani M, Watanabe D.   +3 more
europepmc   +1 more source