Results 51 to 60 of about 117,049 (245)

Hyaluronan-decorated liposomes as drug delivery systems for cutaneous administration

International Journal of Pharmaceutics, 2018
The work aimed to evaluate the feasibility to design hyaluronic acid (HA) decorated flexible liposomes to enhance the skin penetration of nifedipine. Egg phosphatidylcholine (e-PC) based transfersomes (Tween 80) and transethosomes (ethanol) were prepared.
S. Franzè, A. Marengo, B. Stella, P. Minghetti, S. Arpicco, F. Cilurzo   +5 more
openaire   +3 more sources

Immunological Effects of Autogenous Vaccine Administration in Cattle with Cutaneous Papillomatosis

Acta Veterinaria Eurasia, 2020
Papillomavirus is a viral agent that induces the formation of benign tumors in mammals. There are different treatment methods for cutaneous papilloma caused by the bovine papillomavirus (BPV), and one of them is autogenous vaccination. We aimed to investigate the immunological effects of autogenous vaccination in cattle.
GELEN, VOLKAN, AYDIN, Hakan, YILDIRIM, Serkan, ŞENGÜL, Emin   +3 more
openaire   +4 more sources

Engineered MSC Aggregates with E/N‐Cadherin and IL‐6 Preconditioning for the Treatment of Systemic Sclerosis

Advanced Healthcare Materials, EarlyView.
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang, Mengyuan Qian, Yirui Shi, Jiaxu Cao, Min Xu, Xin Wen, Yunxia Yan, Sha Liu, Hongwei Chen, Shanshan Liu, Jun Yang, Lingyun Sun   +11 more
wiley   +1 more source

Penile microvascular endothelial function in hypertensive patients: effects of acute type 5 phosphodiesterase inhibition

Brazilian Journal of Medical and Biological Research, 2018
The primary aim of this study was to evaluate penile endothelial microvascular function in patients with primary arterial hypertension and age-matched normotensive subjects using laser speckle contrast imaging (LSCI).
V. Verri, A.A. Brandão, E. Tibirica
doaj   +1 more source

Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery

Advanced Healthcare Materials, EarlyView.
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis, Joanne Heade, Cristiana Cunha, Marco van de Weert, Lasse Saaby, Stine Rønholt, Hanne Mørck Nielsen   +6 more
wiley   +1 more source

Psychosocial stress enhances IgE-mediated triphasic cutaneous reaction in mice: Antagonism by Yokukan-san (a Kampo medicine) and diazepam

Allergology International, 2001
Background: In the present study, we investigated the effect of social isolation stress on IgE-mediated triphasic cutaneous reactions after 2,4-dinitrofluorobenzene (DNFB) challenge in male BALB/c mice passively sensitized with anti-dinitrophenol (DNP ...
Eiichi Tahara, Wenjuan Wu, Taku Satoh, Tomohiro Yamada, lzumi Kurosaki, Hiroichi Nagai, Shinyu Nunome, Katsutoshi Terasawa, Ikuo Saiki   +8 more
doaj   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

Advanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha, Sneha Kollenchery Ramanathan, Kristin Oskarsdotter, Fatemeh Rasti Boroojeni, Aleksandra Zielińska, Sajjad Naeimipour, Philip Lifwergren, Nina Reustle, Lauren Roberts, Annika Starkenberg, Gunnar Kratz, Peter Apelgren, Karin Säljö, Jonathan Rakar, Lars Kölby, Daniel Aili, Johan Junker   +16 more
wiley   +1 more source

Transdermal drug delivery treatment for overactive bladder

International Brazilian Journal of Urology, 2006
Overactive bladder is commonly treated with oral anticholinergic drugs such as oxybutynin chloride. Although oral anticholinergic agents have been effective in controlling urinary urgency and incontinence, adverse events, particularly dry mouth, often ...
Roger R. Dmochowski, Jonathan S. Starkman, G. Willy Davila   +2 more
doaj   +1 more source

Human Skin Models in Biophotonics: Materials, Methods, and Applications

Advanced Healthcare Materials, EarlyView.
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami, Fabrizio Spano, Kongchang Wei, Mathias Bonmarin, René M. Rossi   +4 more
wiley   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

Advanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang, Sílvio Terra Stefanello, Victor Shahin, Yun Qian   +3 more
wiley   +1 more source