Results 101 to 110 of about 201,578 (196)

Trypstatin as a Novel TMPRSS2 Inhibitor with Broad‐Spectrum Efficacy against Corona and Influenza Viruses

Advanced Science, EarlyView.
Trypstatin, a 61‐amino acid Kunitz‐type protease inhibitor derived from human Bikunin, potently inhibits TMPRSS2 and related proteases. It blocks spike‐ and hemagglutinin‐mediated entry of multiple respiratory viruses in vitro reduces SARS‐CoV‐2 replication in human airway cultures, and lowers viral load and symptoms in infected hamsters, demonstrating
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz, Dan Pascal Jean Albers, Fabian Zech, Julie Vandeput, Lieve Naesens, Giorgio Fois, Veronika Neubauer, Nico Preising, Emilia Schmierer, Yasser Almeida‐Hernandez, Moritz Petersen, Ludger Ständker, Sebastian Wiese, Peter Braubach, Manfred Frick, Eberhard Barth, Daniel Sauter, Frank Kirchhoff, Elsa Sanchez‐Garcia, Annelies Stevaert, Jan Münch   +24 more
wiley   +1 more source

The safety, tolerability, pharmacokinetics, and pharmacodynamics of nebulized pegylated interferon α-2b in healthy adults: a randomized phase 1 trial. [PDF]

BMC Pharmacol Toxicol
Huang W, Kang Y, Zhao Y, Yang J, Dai C, Wu W, Xu J, Jin W, Wu X, Zhou Q.   +9 more
europepmc   +1 more source

Enhancing Sensitivity across Scales with Highly Sensitive Hall Effect‐Based Auxetic Tactile Sensors

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a tactile sensor based on hall‐effect sensors with an auxetic structure, called Hall effect‐based auxetic tactile sensor (HEATS), is proposed. The change in magnetism resulting from the deformation of the auxetic structure is utilized for sensing.
Youngheon Yun, Dongchan Lee, Soyeon Lee, Salvador Pané, Josep Puigmartí‐Luis, Sungwoo Chun, Bumjin Jang   +6 more
wiley   +1 more source

Exogenous GM-CSF therapy for autoimmune pulmonary alveolar proteinosis: a systematic literature review. [PDF]

Front Med (Lausanne)
Chen W, Feng X, Yao LK, Li X, Yang ZM, Qin XY, Li Y, Qiu Y.   +7 more
europepmc   +1 more source

Design, Modeling, and Control of a Soft Robotic Diaphragm‐Assist Device in a Respiratory Simulator

Advanced Intelligent Systems, EarlyView.
A soft robotic diaphragm‐assist device using fabric‐based pneumatic actuators with a 2‐step control system to optimize synchronization and support is introduced. This system can detect the initiation of breathing to trigger assistance and regulate pressures to provide the correct level of inhalation augmentation. Validation and testing are completed on
Diego Quevedo‐Moreno, Sang‐Yoep Lee, Jonathan Tagoe, Vishnu Emani, Jean Bonnemain, Ellen T. Roche   +5 more
wiley   +1 more source

Maternal oxygen inhalation affects the fetal hemodynamic in low-risk with uncomplicated late pregnancy. [PDF]

Eur J Med Res
Wu XQ, Yang XF, Ye L, Zhang XB, Hong YQ, Chiu WH.   +5 more
europepmc   +1 more source

PGI2-Aerosol versus nitric oxide for selective pulmonary vasodilation in hypoxic pulmonary vasoconstriction [PDF]

, 1993
Habazettl, H., Messmer, Konrad, Welte, M., Zwißler, Bernhard   +3 more
core   +1 more source

Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin‐Independent Regulation of Fpn mRNA

American Journal of Hematology, EarlyView.
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu, Sofiya Tsyplenkova, Carine Fillebeen, Kostas Pantopoulos   +3 more
wiley   +1 more source

Preparation of Carrier-Free Inhalable Dry Powder of Rivaroxaban Using Two-Step Milling for Lung-Targeted Delivery. [PDF]

Pharmaceutics
Kim YJ, Son J, Han CS, Park CW.
europepmc   +1 more source

Medical Surveillance of Occupational Lead Exposure Using the EPA's Toxics Release Inventory and Adult Blood Lead Epidemiology and Surveillance Program: Illinois, 2016–2023

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background Despite existing regulations mandating exposure control, training, and monitoring, many worksites continue to inadequately protect workers from lead exposure. The Environmental Protection Agency (EPA) requires facilities to report lead emissions to the Toxics Release Inventory (TRI), presenting a potential tool for identifying at ...
Chibuzor Abasilim, Brett Shannon, Dana Madigan, Lee S. Friedman   +3 more
wiley   +1 more source