Results 91 to 100 of about 2,070,422 (305)

Matrix metalloproteinase 2/9-triggered-release micelles for inhaled drug delivery to treat lung cancer: preparation and in vitro/in vivo studies

International Journal of Nanomedicine, 2018
Xiaofei Wang,1,2 Qinyue Chen,1 Xiaoyan Zhang,1 Xiaoqing Ren,1 Xiulei Zhang,1 Lin Meng,1 Huihui Liang,1 Xianyi Sha,1 Xiaoling Fang1 1Key Laboratory of Smart Drug Delivery, Ministry of Education of China, School of Pharmacy, Fudan University, Shanghai ...
Wang X, Chen Q, Zhang X, Ren X, Zhang X, Meng L, Liang H, Sha X, Fang X   +8 more
doaj  

Inhalation of peptide-loaded nanoparticles improves heart failure [PDF]

, 2018
Peptides are highly selective and efficacious for the treatment of cardiovascular and other diseases. However, it is currently not possible to administer peptides for cardiac-targeting therapy via a non- invasive procedure, thus representing scientific ...
Paola Ceriotti, Pierluigi Carullo, Patrício, Tatiana, Iafisco, Michele, Vacchiano, Marco, Rossi, Stefano, Erreni, Marco, Condorelli, Gianluigi, Alessio Alogna, Gianluigi Condorelli, Catalucci, Daniele, Lorenzo Degli Esposti, Daniele Catalucci, Fernandes Patrício, Tatiana Marisa, Gloria Belén Ramirez-Rodríguez, DEGLI ESPOSTI, LORENZO, Marco Erreni, Anna Tampieri, Francesca Ravanetti, Michele Miragoli, Rossella Alinovi, Marco Vacchiano, Tampieri, Anna, Nicolò Salvarani, Stefano Rossi, Alogna, Alessio, Ramirez-Rodríguez, Gloria Belén, Michele Iafisco, Miragoli, Michele, Pinelli, Silvana, Post, Heiner, Silvana Pinelli, Alinovi, Rossella, Ramírez-Rodríguez, Gloria Belén, Tatiana Patrício, Francesca Rossi, Salvarani, Nicolò, Ravanetti, Francesca, Heiner Post, Rossi, Francesca, Salvarani, NicolÃ2, Carullo, Pierluigi, Ceriotti, Paola, Patricio, Tatiana, Ravanetti F., Rossi F., Erreni M., Post H., Carullo P., Alogna A., Salvarani N., Alinovi R., Degli Esposti L., Miragoli M., Catalucci D., Iafisco M., Esposti, Lorenzo Degli, Condorelli G., Vacchiano M., Tampieri A., Ceriotti P., Ramirez-Rodriguez G. B., Patricio T., Pinelli S., Rossi S., Gloria Belén RamirezRodríguez   +65 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Effect of Kaempferol on Cyclooxygenase 2 (Cox2) and Cytosolic Phospholipase A2 (cPLA2) Protein Expression in BALB/c Mice

Iranian Journal of Allergy, Asthma and Immunology, 2018
Kaempferol, a phytochemical found in many edible plants, is known to alleviate diseases such as cancer, allergy, and inflammation. The objective of this study was to investigate whether kaempferol could reduce omega-6 and ovalbumin-mediated allergic ...
Da Rae Kang, Shah Ahmed Belal, Ho Sung Choe, Dae Keun Shin, Kwan Seob Shim   +4 more
doaj   +1 more source

Inhalation anesthesia [PDF]

In this paper I will give a somewhat brief report of the high lights of the history of anaesthesia, followed by a generalized description of the various general inhalation anesthetics, their action on the human organism, and the administration of these ...
Baldwin, Ellen
core   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

THE "IDEAL" INHALER FOR THE ADMINISTRATION OF SOMNOFORM AND ALLIED ANÆSTHETICS. [PDF]

The Lancet, 1903
n ...
openaire   +1 more source

E-cigarettes: Learnings for inhalation scientists: How studying e-cigarette technology may lead to new inhalation therapies

, 2016
ECs share a common purpose with conventional pharmaceutical inhalation devices: they produce aerosols intended to be orally inhaled into the respiratory tract.
Kwok, PCL, Hou, L, Rogueda, P
core  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant Pseudomonas aeruginosa

BMC Infectious Diseases, 2011
Background Colistin is used as last treatment option for pneumonia associated with multidrug-resistant (MDR) Pseudomonas spp.. Literature about the best administration mode (inhalation versus parenteral treatment) is lacking.
Naesens Reinout, Vlieghe Erika, Verbrugghe Walter, Jorens Philippe, Ieven Margareta   +4 more
doaj   +1 more source