Results 21 to 30 of about 2,696,581 (351)

Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury.

open access: yesJournal of Controlled Release, 2022
Mesenchymal stem cell-derived small extracellular vesicles (MSC-EVs) are promising nanotherapeutic agent for pneumonia (bacterial origin, COVID-19), but the optimal administration route and potential mechanisms of action remain poorly understood.
Rui Zhao   +5 more
semanticscholar   +1 more source

Particle engineering in dry powders for inhalation.

open access: yesEuropean Journal of Pharmaceutical Sciences, 2022
Drug administration by inhalation is a well-established approach to treat respiratory and systemic diseases. To deliver a drug into the lung dry powder inhalation (DPI) is an advantageous, but yet challenging option.
R. Scherließ   +4 more
semanticscholar   +1 more source

Aerosol Inhalation of Heat-Killed Clostridium butyricum CGMCC0313-1 Alleviates Allergic Airway Inflammation in Mice

open access: yesJournal of Immunology Research, 2022
Epidemiological studies have shown that exposure to beneficial microorganisms can reduce the risk of asthma, but the clinical use of live probiotics is controversial due to the risk of infection.
Laodong Li   +7 more
doaj   +1 more source

Medication Administration With Inhalers or Nebulizers

open access: yesCanadian Journal of Health Technologies, 2021
Delivery of medication via metered-dose inhalers to children or adults with asthma, or adults with chronic obstructive pulmonary disease at emergency departments or intensive care units, may be as effective as nebulizers in terms of clinical parameters and health care resource use. Limited data on adverse events showed no significant ...
Khai Than, Aleksandra Grobelna
openaire   +2 more sources

Intratracheal administration of polystyrene microplastics induces pulmonary fibrosis by activating oxidative stress and Wnt/β-catenin signaling pathway in mice.

open access: yesEcotoxicology and Environmental Safety, 2022
Polystyrene microplastics (PS-MPs) are emerging pollutants that are absorbed by organisms. Due to their small volume and strong biological permeability, they affect the biological functions of cells.
Xuran Li   +7 more
semanticscholar   +1 more source

Inhalation monoclonal antibody therapy: a new way to treat and manage respiratory infections

open access: yesApplied Microbiology and Biotechnology, 2021
The route of administration of a therapeutic agent has a substantial impact on its success. Therapeutic antibodies are usually administered systemically, either directly by intravenous route, or indirectly by intramuscular or subcutaneous injection ...
H. A. Parray   +12 more
semanticscholar   +1 more source

Oral inhalation for delivery of proteins and peptides to the lungs.

open access: yesEuropean journal of pharmaceutics and biopharmaceutics, 2021
Oral inhalation is the preferred route for delivery of small molecules to the lungs, because high tissue levels can be achieved shortly after application.
E. Fröhlich, S. Salar-Behzadi
semanticscholar   +1 more source

Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing

open access: yesFrontiers in Pharmacology, 2022
To avoid adverse drug reactions associated with injection, off-label nebulization of Tanreqing (TRQ) injection is often used in China to treat respiratory diseases.
Teng-Fei Chen   +11 more
doaj   +1 more source

Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection

open access: yesPharmaceutics, 2021
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has produced a global pandemic. As of 22 June 2021, 178 million people have been affected worldwide, and 3.87 million people have died from COVID-19. According to the Centers
Basanth Babu Eedara   +5 more
semanticscholar   +1 more source

Developmental toxicity of combined ethylbenzene and methylethylketone administered by inhalation to rats [PDF]

open access: yes, 2006
Pregnant Sprague–Dawley rats were exposed to ethylbenzene (EB; 0, 250, or 1000 ppm) and methylethylketone (MEK; 0, 1000, or 3000 ppm), alone and in combination, by inhalation, for 6 h/day, during days 6–20 of gestation.
Cadot, R.   +6 more
core   +1 more source

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