Results 41 to 50 of about 2,070,422 (305)

Evaluation of asthma control, parents’ quality of life and preference between AeroChamber Plus and AeroChamber Plus Flow-Vu spacers in young children with asthma [PDF]

open access: yes, 2015
Objective: The AeroChamber Plus (AC) valved holding chamber has been enhanced to include the Flow-Vu (FV) inspiratory flow indicator that provides visual inhalation feedback during use. We have investigated if FV alters asthma control and whether parents
Toor, Sophie   +5 more
core   +1 more source

Clinical efficacy of dexmedetomidine combined with sevoflurane sedation in pediatric MRI scanning

open access: yesDi-san junyi daxue xuebao, 2020
Objective To observe the sedation effect and safety of intranasal dexmedetomidine in combination with sevoflurane inhalation for pediatric patients undergoing magnetic resonance imaging(MRI).
ZHANG Tiange   +5 more
doaj   +1 more source

Inhalation therapy in children [PDF]

open access: yes, 2014
Inhalation is a form of treatment used in respiratory diseases that allows medications to be administered directly to the affected site. Thanks to this, the administration of lower doses helps obtain a higher concentration in the target organ and ...
Jolanta Pietrzak   +5 more
core   +1 more source

Factors Affecting Drug Exposure after Inhalation

open access: yesPrague Medical Report, 2022
Administration of drugs by inhalation is mainly used to treat lung diseases and is being investigated as a possible route for systemic drug delivery. It offers several benefits, but it is also fraught with many difficulties.
Anežka Nováková   +2 more
doaj   +1 more source

Comparison of blood toluene levels after inhalation and oral administration [PDF]

open access: yes, 1988
The purpose of this investigation was to compare blood toluene levels in Sprague-Dawley rats after oral and inhalation administration. Groups of 30 rats were dosed by gavage with 86.7, 217, 433, or 867 mg toluene/kg body wt or exposed for up to 6 hr, 5 ...
Conolly, Rory B., Sullivan, Michael J.
core   +4 more sources

Suppression of Dextran Sulfate Sodium-Induced Colitis in Mice by Radon Inhalation

open access: yesMediators of Inflammation, 2012
The enhanced release of reactive oxygen species from activated neutrophils plays important role in the pathogenesis of inflammatory bowel disease. We previously reported that radon inhalation activates antioxidative functions in various organs of mice ...
Yuichi Nishiyama   +4 more
doaj   +1 more source

Metabolism of verapamil in cultures of rat alveolar epithelial cells and pharmacokinetics after administration by intravenous and inhalation routes

open access: yes, 2022
S.1108-1114Administration of therapeutic entities by inhalation opens new possibilities for drug entry into systemic circulation, but this requires passage through the alveolar epithelium.
Levsen, K.   +5 more
core   +1 more source

Inhaler device, administration technique, and adherence to inhaled corticosteroids in patients with asthma [PDF]

open access: yesPrimary Care Respiratory Journal, 2011
To compare inhaled corticosteroid (ICS) inhaler type with user technique and ICS medication adherence among adults with asthma.We classified 270 adults into two groups by ICS device type: metered-dose inhaler (MDI) or dry powder inhaler (DPI). Inhaler technique was assessed using standardised checklists.
Angkana, Roy   +4 more
openaire   +2 more sources

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Inhalation of itraconazole mitigates bleomycin-induced lung fibrosis via regulating SPP1 and C3 signaling pathway pivotal in the interaction between phagocytic macrophages and diseased fibroblasts

open access: yesJournal of Translational Medicine
Background Idiopathic pulmonary fibrosis (IPF) stands as a significant contributor to global mortality rates. Presently, there exists a dearth of effective anti-fibrotic treatments for this condition.
Caizhe Pan   +10 more
doaj   +1 more source

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