Results 271 to 280 of about 96,743 (331)

Single‐Dose Pharmacokinetics of Intranasal Levetiracetam in Healthy Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Cluster seizures and status epilepticus in dogs are emergencies requiring rapid intervention. Intranasal (IN) benzodiazepines are effective for early seizure cessation, but the pharmacokinetics of longer‐acting antiseizure medications administered IN have not been investigated in dogs.
Jessica L. Wagner, Kari D. Foss, Jennifer M. Reinhart, Lauren E. Forsythe   +3 more
wiley   +1 more source

Efficacy and Safety of Dexmedetomidine Nasal Spray as a Premedication in Patients Undergoing Fiberoptic Bronchoscopy Under Sedation: A Randomized Controlled Trial. [PDF]

Drug Des Devel Ther
Zhao G, Qin W, Wu J, Wei S, Jiang X, Qiu H, Du X, Chen L.   +7 more
europepmc   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim, Andy Cano Tran, Ju Kim, Humblenoble Stembridge Ayuk, Adam Sparrow, Lorenzo Bossi, Megan Brown, Emil Joseph Vergara, Kathrin Göritzer, Elisabetta Groppelli, Tae‐Ho Kwon, Julian K. C. Ma, Yong‐Suk Jang, Rajko Reljic   +13 more
wiley   +1 more source

Liver Transplantation in PNPO Deficiency: Management Challenges and Biological Lessons. [PDF]

JIMD Rep
Webster R, Sankaran BP, Bandodkar S, Stormon M, Thomas G, Shun A, Bowen DG, Fielder T, Barclay P, Khalil Y, Mills P, Clayton P, Bhattacharya K.   +12 more
europepmc   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Oxytocin: a neglected hormone in pituitary disease - From function to the diagnosis of a deficiency, resulting clinical relevance, and potential treatment options in endocrinology. [PDF]

Arch Endocrinol Metab
Leibnitz S, Christ-Crain M, Atila C.
europepmc   +1 more source

Successful Treatment of Acute Respiratory Distress Syndrome in an 8‐Day‐Old Standardbred Foal With Intratracheal Oxygen Therapy via Temporary Tracheostomy

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective This report describes an 8‐day‐old foal diagnosed with acute respiratory distress syndrome (ARDS) successfully managed using a novel approach of intratracheal oxygen delivery. Case Summary An 8‐day‐old Standardbred filly presented for an acute onset of respiratory distress. Given the acute onset, known risk factors, bilateral diffuse
Megan G. Palmisano, Caitlyn R. Tukdarian, Klaus Hopster, Rose D. Nolen‐Walston   +3 more
wiley   +1 more source

Advances and prospects of respiratory mucosal vaccines: mechanisms, technologies, and clinical applications. [PDF]

NPJ Vaccines
Li J, Wu G, Huang Z, Hu J, Tie X, Wu H, Wang Z, Chen K.   +7 more
europepmc   +1 more source

Successful Management of a Refractory Orbital Pseudocyst in a Chinese Goose Using Intraorbital Gentamicin Injection

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To report the successful management of recurrent orbital swelling in a Chinese goose (Anser cygnoides ) following evisceration surgery, utilizing intraorbital gentamicin injection after multiple unsuccessful interventions. Animal Studied A 3‐year‐old, 4.58 kg male Chinese goose (Anser cygnoides ).
Kristopher Houston, Chloe Fontaine, Natalia Dziedzic‐Nyrka, David Donaldson   +3 more
wiley   +1 more source

Intranasal insulin and postoperative delirium in adult surgical patients: a meta-analysis and systematic review of randomized controlled trials. [PDF]

Front Med (Lausanne)
Zhang LC, Song JL, Qiu LQ, Li Q, Yu X, Lu B, Chen GY.   +6 more
europepmc   +1 more source