Results 31 to 40 of about 1,796,663 (223)

Intravaginal administration of metformin HCL loaded nanoemulgel for treatment of PCOS: in-vitro and in-vivo study [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences
Metformin HCL (MET-HCL), is a Biguanide derivative, most effective agent in treatment of PCOS. The focus of the present study was on developing and optimizing a nanoemulsion formulation.
Mukesh Ratnaparkhi   +7 more
doaj   +2 more sources

Bonneville Power Administration 1998 Annual Report.

open access: yes, 1998
This is the 1998 annual report to the President by the Administrator and Chief Executive Officer of the Bonneville Power Administration. The topics of the report include financial highlights, letter to the President, review of 1998, financial data ...
United States. Bonneville Power Administration.
core   +1 more source

Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties: preparation, characterization and application in a vaginal drug delivery system

open access: yesActa Pharmaceutica Sinica B, 2017
Lack of mucoadhesive properties is the major drawback to poloxamer 407 (F127)-based in situ hydrogels for mucosal administration. The objective of the present study was to construct a novel mucoadhesive and thermosensitive in situ hydrogel drug delivery ...
Liqian Ci   +5 more
doaj   +1 more source

Heterologous prime-boost vaccination based on Polymorphic protein D protects against intravaginal Chlamydia trachomatis infection in mice

open access: yesScientific Reports, 2022
The control of the worldwide spread of sexually transmitted Chlamydia trachomatis (Ct) infection urgently demands the development of a preventive vaccine.
Romina Cecilia Russi   +6 more
doaj   +1 more source

Intravaginal Gel for Sustained Delivery of Occidiofungin and Long-Lasting Antifungal Effects

open access: yesGels, 2023
Fungal infections are caused by opportunistic pathogens that can be life threatening or debilitating. Candida spp. are becoming increasingly resistant to current clinically approved antifungal therapeutics.
Andrew Cothrell   +5 more
doaj   +1 more source

Abortion caused by intravaginal self-administration of Misoprostol: a case report

open access: yesRomanian Journal of Legal Medicine, 2019
The authors present a case of a 38 years old woman, 21 weeks pregnant, that went to the emergency department, where she gave birth to a stillborn male fetus. A gynaecological examination revealed three partially dissolved tablets in the vagina. Chemical laboratory tests on the tablets showed they were Misoprostol (MP) tablets.
Martina Focardi   +5 more
openaire   +2 more sources

Utility of Pelvic Floor Therapy and Behavioral Interventions in the Neurogenic Lower Urinary Tract Dysfunction (NLUTD) Population

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims Neurogenic lower urinary tract dysfunction (NLUTD) describes a wide range of symptoms depending on neurologic diagnosis and the resulting bladder and sphincter dysfunction. This narrative review is designed to address the question regarding which NLUTD population benefits most from pelvic floor therapy and behavioral interventions, and ...
Sara M. Lenherr
wiley   +1 more source

Design, development and optimisation of veterinary intravaginal controlled release drug delivery systems [PDF]

open access: yes, 2014
This Thesis begins by discussing the application of controlled drug delivery to the intravaginal delivery of hormones to control the oestrous cycle of farmed animals, with particular emphasis on the delivery of progestagens to cattle and sheep.
Ogle, Colin Roger
core  

Determination of fenticonazole in human plasma by HPLC–MS/MS and its application to pharmacokinetic studies

open access: yesJournal of Pharmaceutical Analysis, 2017
Two simple and sensitive high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) methods were developed and validated for the determination of fenticonazole in human plasma after percutaneous and intravaginal administration ...
Weixing Mao   +5 more
doaj   +1 more source

Sorafenib Nanomicelles Effectively Shrink Tumors by Vaginal Administration for Preoperative Chemotherapy of Cervical Cancer

open access: yesNanomaterials, 2021
To investigate the potential of sorafenib (SF) in preoperative chemotherapy for cervical cancer to reduce tumor volume, sorafenib micelles (SF micelles) with good stability and high drug loading were designed.
Jun Wang   +6 more
doaj   +1 more source

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