Results 21 to 30 of about 1,796,663 (223)

Intravaginal lactic Acid bacteria modulated local and systemic immune responses and lowered the incidence of uterine infections in periparturient dairy cows. [PDF]

open access: yesPLoS ONE, 2014
The objective of this investigation was to evaluate whether intravaginal infusion of a lactic acid bacteria (LAB) cocktail around parturition could influence the immune response, incidence rate of uterine infections, and the overall health status of ...
Qilan Deng   +5 more
doaj   +1 more source

Intravaginal hormonal contraception for women of reproductive age with excessive body mass

open access: yesZaporožskij Medicinskij Žurnal, 2015
There are a number of disadvantages inherent in all oral hormonal contraceptives: need for daily administration, fluctuations of hormone levels throughout the day, metabolism in the gastrointestinal tract, the effect of the first passage through the ...
I. B. Gridina
doaj   +1 more source

Continuous acceleration of neural activity of the GnRH pulse generator during chronic peripheral infusion of neurokinin 3 receptor agonist in goats

open access: yesThe Journal of Reproduction and Development, 2023
Secretion of pulsatile gonadotropin-releasing hormone (GnRH) is essential for reproduction. Kisspeptin neurons in the arcuate nucleus (ARC), which coexpress neurokinin B (NKB) and its receptor (NK3R), are believed to be components of the GnRH pulse ...
Takashi YAMAMURA   +2 more
doaj   +1 more source

Tolerable toxicity after repeated intravaginal administration of IL-7-Fc. from Intravaginal Administration of Fc-Fused IL7 Suppresses the Cervicovaginal Tumor by Recruiting HPV DNA Vaccine-Induced CD8 T Cells

open access: yes, 2016
Supplementary Table 1. Tolerable toxicity after repeated intravaginal administration of IL-7-Fc. Information of detailed materials and methods, and supplementary figure legends are contained.
Yong Bok Seo (8605218)   +9 more
core   +2 more sources

Enhanced Delivery of Imatinib into Vaginal Mucosa via a New Positively Charged Nanocrystal-Loaded in Situ Hydrogel Formulation for Treatment of Cervical Cancer

open access: yesPharmaceutics, 2019
The present study was carried out to investigate the potential of cationic functionalization on imatinib nanocrystals to improve the mucoadhesiveness and, thus, delivery to the lesion of cervicovaginal tumors.
Li-qian Ci   +10 more
doaj   +1 more source

Low Immunogenicity of Intravesical Phage Therapy for Urogenitary Tract Infections

open access: yesAntibiotics, 2021
Patients with chronic urinary and urogenital multidrug resistant bacterial infections received phage therapy (PT) using intravesical or intravesical and intravaginal phage administration.
Sławomir Letkiewicz   +5 more
doaj   +1 more source

Influence of administration of Staphylococcus aureus cells suspension on composition of vaginal microflora of mice under immunosupression

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
The influence of intravaginal administration of cells of indigenous strain of Staphylococcus aureus on composition of vaginal microbiocenosis was studied.
O. S. Voronkova   +3 more
doaj   +1 more source

Research of acute toxicity of the drug HEXIA

open access: yesФармацевтичний журнал, 2018
Diseases of the genitourinary system caused by pathogenic and potentially pathogenic microorganisms, which result into disbiosis of urinary organs, remain an urgent problem of dermatovenereology, gynecology and urology, despite the fact that there is a ...
V. L. Karbovskyy   +3 more
doaj   +1 more source

Development and Evaluation of a Thermosensitive In Situ Gel Formulation for Intravaginal Delivery of Lactobacillus gasseri

open access: yesPharmaceutics, 2022
In situ administration of vaginal probiotics has been proposed as an effective prevention strategy against gynecological diseases caused by microecological disorders.
Ye Zhao   +7 more
doaj   +1 more source

Development of 3D-printed vaginal devices containing metronidazole for alternative bacterial vaginosis treatment

open access: yesInternational Journal of Pharmaceutics: X, 2023
Bacterial vaginosis (BV) is an abnormal condition caused by the change of microbiota in the vagina. One of the most common bacteria found in the case of BV is Gardnerella vaginalis, which is categorised as anaerobic facultative bacteria.
Emilia Utomo   +7 more
doaj   +1 more source

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