Results 21 to 30 of about 493,126 (165)

Evaluation of pharmacokinetics underlies the collaborated usage of lamivudine and oxymatrine in beagle dogs

Asian Journal of Pharmaceutical Sciences, 2016
Combinational therapy of lamivudine and oxymatrine has been employed in the battle against hepatitis B virus in clinical setting. However, the pharmacokinetic behavior of the drug or active metabolism in intravenous/oral co-administration regime is ...
Zhenbao Li, Lei Shang, Chang Liu, Panqin Ma, Chunnuan Wu, Wenjuan Zhang, Yinghua Sun, Yongjun Wang, Xiaohong Liu, Jin Sun   +9 more
doaj   +1 more source

Efficacy and safety of subcutaneous and intravenous rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in first-line diffuse large B-cell lymphoma: the randomized MabEase study

Haematologica, 2017
Intravenous rituximab plus chemotherapy is standard treatment for diffuse large B-cell lymphoma. A subcutaneous formulation of rituximab is expected to simplify and shorten drug preparation and administration, and to reduce treatment burden.
Pieternella Lugtenburg, Irit Avivi, Henriette Berenschot, Osman Ilhan, Jean Pierre Marolleau, Arnon Nagler, Antonio Rueda, Monica Tani, Mehmet Turgut, Stuart Osborne, Rodney Smith, Michael Pfreundschuh   +11 more
doaj   +1 more source

Acceptability of intramuscular injection of tranexamic acid in postpartum hemorrhage preventionAJOG Global Reports at a Glance

AJOG Global Reports, 2023
BACKGROUND: Newer research comparing routes of medication administration has extended beyond efficacy as a primary endpoint to incorporate patient preference.
Sophia A. Cordes, BS, Alexandra R. Nesson, BA, Joaquin Calderon, MD, Dinan S. Abdelatif, MPH, Homa K. Ahmadzia, MD, MPH   +4 more
doaj   +1 more source

Efficacy of scheduled intravenous acetaminophen administration for catheter-related bladder discomfort in patients after transurethral resection of bladder tumors: A prospective randomized pilot study [PDF]

Investigative and Clinical Urology
Purpose: Scheduled administration of intravenous acetaminophen improves catheter-related bladder discomfort (CRBD) after urological surgery. However its efficacy for patients undergoing transurethral resection of bladder tumors (TURBT) remains unclear ...
Tomoya Hatayama, Koji Mita, Yuki Kohada, Kenta Fujiyama, Ryo Tasaka, Akihiro Goriki, Hideki Mochizuki , Nobuyuki Hinata   +7 more
doaj   +1 more source

Development of Sedative Dexmedetomidine Sublingual In Situ Gels: In Vitro and In Vivo Evaluations

Pharmaceutics, 2022
Intravenous dexmedetomidine (DEX) is currently approved by the FDA for the sedation of intubated patients in intensive care units to reduce anxiety and to augment postoperative analgesia.
Ayat A. Allam, Nermin E. Eleraky, Nadeen H. Diab, Mahmoud Elsabahy, Sahar A. Mohamed, Hala S. Abdel-Ghaffar, Nivin A. Hassan, Samia A. Shouman, Mervat M. Omran, Sahar B. Hassan, Noura G. Eissa   +10 more
doaj   +1 more source

Risk factors for linezolid-associated hyponatremia focused on differences between intravenous and oral administration: a single-center, retrospective study

Journal of Pharmaceutical Health Care and Sciences
Background Linezolid (LZD)-associated hyponatremia is a rare side effect, and no reports have compared intravenous and oral administration in relation to the development of hyponatremia.
Ryoji Takata, Masatoshi Taga, Hirofumi Nagai, Yoshihiro Nishita, Hironori Kobayashi, Nozomi Arakawa, Toru Imai, Yoshitsugu Iinuma, Togen Masauji   +8 more
doaj   +1 more source

Intranasal Sufentanil versus Intravenous Morphine Sulfate in Pain Management of Patients with Extremity Trauma

طب اورژانس ایران, 2015
Introduction: Pain is one of the most common complaints of patients referred to emergency department (ED) and its control is one of the most important responsibilities of the physicians. The present study was designed, aiming to compare the efficiency of
Ali Arhami Dolatabadi, Majid Shojaee, Afshin Amini, Hojjat Derakhshanfar, Seyed Mohammad Hosseini, Davood Gallehdar   +5 more
doaj  

Pharmacokinetic Interaction Between Oltipraz and Silymarin in Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2009
. Purpose: To evaluate the pharmacokinetic interaction between oltipraz and silymarin after intravenous and oral administration of both drugs to male Sprague–Dawley rats.
Min Kyung Kang, Soo Kyung Bae, Jin Wan Kim, Myung Gull Lee   +3 more
doaj   +1 more source

Intravenous Voriconazole after Toxic Oral Administration [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT In a male patient with rhinocerebral invasive aspergillosis, prolonged high-dosage oral administration of voriconazole led to hepatotoxicity combined with a severe cutaneous reaction while intravenous administration in the same patient did not.
Alffenaar, J.W.C., Van Assen, S., De Monchy, J.G.R., Uges, D.R.A., Kosterink, J.G.W., Van Der Werf, T.S.   +5 more
openaire   +2 more sources

Recurrent severe hypophosphatemia following intravenous iron administration

Clinical Case Reports, 2020
Key Clinical Message Hypophosphatemia postintravenous iron is frequent but under‐recognized. If prolonged or recurrent, it can cause osteomalacia. The likely mechanisms are direct toxicity to proximal tubular cells causing phosphate wasting, elevated ...
Melissa Stephanie Nataatmadja, Ross Francis   +1 more
doaj   +1 more source