Results 21 to 30 of about 4,385,684 (306)
Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid
Pharmaceutics, 2021 Mycophenolic acid (MPA) is commonly used for organ rejection prophylaxis via oral administration in the clinic. Recent studies have shown that MPA also has anticancer activities. To explore new therapeutic options for oral precancerous/cancerous lesions,
Xiuqing Gao +7 more
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No relation between docetaxel administration route and high‐grade diarrhea incidence
Pharmacology Research & Perspectives, 2020 Oral administration of docetaxel in combination with the CYP3A4 inhibitor ritonavir is used in clinical trials to improve oral bioavailability of docetaxel. Diarrhea was the most commonly observed and dose‐limiting toxicity.
Jeroen J. M. A. Hendrikx +9 more
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Oral Administration of Bacitracin
Experimental Biology and Medicine, 1948 SummaryFrom the small series of animals receiving oral bacitracin, the following significant facts were obtained: 1. Fecal streptococci and spore forming anaerobes were greatly reduced in the intestine at a dosage between 2,000 and 10,000 u/kg per day. 2. Coliform organisms were little affected by bacitracin. 3.
G. C. Bond +3 more
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GENERAL ANALGESIA BY ORAL ADMINISTRATION [PDF]
BMJ, 1918 This report is in the nature of a preliminary communication based on animal experiments and a sufficient number of clinical cases to support the conclusions of the animal work. It will be seen that general analgesia in which there is loss of sensation, with or without loss of consciousness, can be established for otherwise painful dressings and for ...
J T, Gwathmey, H T, Karsner
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Prescription drug forms with midazolam [PDF]
Farmacja Polska, 2021 Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
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Oral Administration of Salecan-Based Hydrogels for Controlled Insulin Delivery.
Journal of Agricultural and Food Chemistry, 2018 We present an improved type of food gum (salecan) based hydrogels for oral delivery of insulin. Structural hydrogel formation was assessed with Fourier transform infrared spectroscopy, thermogravimetric analysis, and X-ray diffraction.
Xiaoliang Qi +4 more
semanticscholar +1 more source
Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome
Msphere, 2018 Increasing evidence suggest that alterations of the gut microbiome underlie metabolic disease pathology by modulating gut metabolite profiles. We have shown that orally administered Porphyromonas gingivalis, a representative periodontopathic bacterium ...
Tamotsu Kato +7 more
semanticscholar +1 more source
Oral administration of pyrophosphate inhibits connective tissue calcification
EMBO Molecular Medicine, 2017 Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in ABCC6 and ENPP1, respectively, present with extensive tissue calcification due to reduced ...
D. Dedinszki +12 more
semanticscholar +1 more source
Patient Preference and Adherence, 2016 Objective The emergence of various modes of administration for cancer treatment, including oral administration, brings into focus the importance of patient preference for administration.
D. Eek +6 more
semanticscholar +1 more source
The adjuvant effect of bacterium-like particles depends on the route of administration
Frontiers in Immunology, 2023 Direct administration of vaccines to mucosal surfaces, such as via oral or nasal vaccination, represents an attractive alternative, or complement, to current parenteral vaccination because it has a potential to induce antigen-specific immunity both at ...
Haruka Sudo +8 more
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