Results 31 to 40 of about 4,385,684 (306)

Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors

open access: yesFrontiers in Pharmacology, 2020
The oral route is by far the most common route of drug administration in the gastrointestinal tract and can be used for both systemic drug delivery and for treating local gastrointestinal diseases.
S. Hua
semanticscholar   +1 more source

Nursing students’ perceptions of clinical learning opportunities and competence in administration of oral medication in the Western Cape

open access: yesCurationis, 2020
Background: Medication errors may result in patients’ harm and even death. The improvement of nursing students’ competence in the administration of medication through education and training can contribute to the reduction of medication errors ...
John J. Musafiri, Felicity Daniels
doaj   +1 more source

Effects of BCL oral administation and herbal acupuncture at BL18, BL19 on Liver function changes induced by Alcohol in the mice

open access: yesJournal of Pharmacopuncture, 2002
This dissertation was designed to evaluate the effect of BCL(refinded Bambusae Caulis in Liqua-men) oral administration and herbal acupuncture on alcohol metabolism and liver function. For this study.
Sa-Hyun Park
doaj   +1 more source

Methotrexate efficacy and tolerability after switching from oral to subcutaneous route of administration in juvenile idiopathic arthritis

open access: yesRheumatology, 2016
Objectives : Methotrexate (MTX) is one of the most frequently used, highly effective disease-modifying drugs in juvenile idiopathic arthritis (JIA) therapy.
Zbigniew Żuber   +6 more
doaj   +1 more source

Broncho-Vaxom attenuates allergic airway inflammation by restoring GSK3β-related T regulatory cell insufficiency. [PDF]

open access: yesPLoS ONE, 2014
Oral administration of bacterial extracts (eg, Broncho-Vaxom (BV)) has been proposed to attenuate asthma through modulating Treg cells. However, the underlying mechanism has not been fully characterized.
Ran Fu   +8 more
doaj   +1 more source

Challenges and Recent Progress in Oral Drug Delivery Systems for Biopharmaceuticals

open access: yesPharmaceutics, 2019
Routes of drug administration and the corresponding physicochemical characteristics of a given route play significant roles in therapeutic efficacy and short term/long term biological effects.
B. Homayun, Xueting Lin, Hyo-Jick Choi
semanticscholar   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale   +6 more
wiley   +1 more source

Enhanced Bioavailability of Tadalafil after Intranasal Administration in Beagle Dogs

open access: yesPharmaceutics, 2018
Tadalafil is an oral selective phosphodiesterase type-5 inhibitor with demonstrated efficacy and safety that is used to treat erectile dysfunction. The purpose of this study is to compare the pharmacokinetic properties of tadalafil after conventional ...
Jeong-Soo Kim, Min-Soo Kim, In-hwan Baek
doaj   +1 more source

Nano and Microparticles as Potential Oral Vaccine Carriers and Adjuvants Against Infectious Diseases

open access: yesFrontiers in Pharmacology, 2021
Mucosal surfaces are the first site of infection for most infectious diseases and oral vaccination can provide protection as the first line of defense. Unlike systemic administration, oral immunization can stimulate cellular and humoral immune responses ...
S. D. Jazayeri   +4 more
semanticscholar   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard   +8 more
wiley   +1 more source

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