Results 41 to 50 of about 34,531 (282)

Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration

Frontiers in Pharmacology, 2019
The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
doaj   +1 more source

Misoprostol administered sublingually at a dose of 12.5 μg versus vaginally at a dose of 25 μg for the induction of full-term labor: a randomized controlled trial

Reproductive Health, 2020
Background Labor induction is defined as any procedure that stimulates uterine contractions before labor begins spontaneously. The vaginal and oral routes of administration of misoprostol are those most used for the induction of labor in routine practice,
Daniele S. M. B. Gattás, Melania M. R. de Amorim, Francisco E. L. Feitosa, José R. da Silva-Junior, Lívia C. G. Ribeiro, Gustavo F. A. Souza, Alex S. R. Souza   +6 more
doaj   +1 more source

Advances in oral transmucosal drug delivery [PDF]

, 2011
Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc, Liu, Fang, Patel, Viralkumar F.   +2 more
core   +1 more source

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]

, 2019
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus, Boot, Johan D, de Kam, Pieter-Jan, Džupinová, Mária, Klimek, Ludger, Kuna, Piotr, Opstelten, Dirk Jan E, Panzner, Petr, Pfaar, Oliver, van Nimwegen, Maroesja J, Yu, Donghui   +10 more
core   +2 more sources

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Diltiazem alone and combined with nitroglycerin: effect on normal and diseased human coronary arteries [PDF]

, 2017
The vasodilatory effect of diltiazem and nitroglycerin on the large epicardial coronary arteries was evaluated in 26 patients with coronary artery disease.
Bortone, A., Gage, J. E., Grimm, J., Hess, O. M., Krayenbuehl, H. P., Nonogi, H.   +5 more
core  

Local Specific IgE Levels Can Predict and Monitor the Therapeutic Response to Subcutaneous Immunotherapy With House Dust Mite

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Identifying predictive and monitoring biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to investigate the systemic and local levels of immunoglobulins and identify potential biomarkers in house dust mite (HDM) allergic rhinitis (AR) patients who are undergoing subcutaneous ...
Xu Xu, Jingyun Li, Xu Zhang, Yu Song, Lin Xi, Luo Zhang, Yuan Zhang   +6 more
wiley   +1 more source

Comparison of the efficacy of sublingual, oral, and vaginal administration of misoprostol in the medical treatment of missed abortion during first trimester of pregnancy: A randomized clinical trial study

Journal of Research in Medical Sciences, 2020
Background: This study was aimed at comparing the efficacy of different routes of misoprostol administration, including sublingual, oral, and vaginal, on the induction of medical abortion in the first trimester of pregnancy.
Behnaz Souizi, Rahim Akrami, Fateme Borzoee, Mohammad Sahebkar   +3 more
doaj   +1 more source

The challenge of perioperative pain management in opioid-tolerant patients [PDF]

, 2017
The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals.
Bifulco, F, Coluzzi, Flaminia, Corcione, A., Cuomo, A, Dauri, M, Leonardi, C, Melotti, Rm, Natoli, S, Romualdi, P, Savoia, G   +9 more
core   +2 more sources

Effect of Laser Posterior Nasal Neurolysis for the Treatment of Chronic Rhinitis: A Randomized Controlled Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background To determine the safety and efficacy of laser ablation of the posterior nasal nerve (PNN) for the treatment of chronic rhinitis. Methods This study was a single‐center, prospective, single‐blinded, randomized sham‐controlled trial. Patients with a 24‐h reflective Total Nasal Symptom Score (rTNSS) ≧ 5, rhinorrhea ≧ 2, and congestion ≧
Jyun‐Yi Liao, En‐Ying Wang, Ying‐Shuo Hsu, Ming‐Shao Tsai, Cheng‐Jung Wu, Chia‐Hao Chang, Yi‐Li Hwang, Han‐Lo Teng, Jun‐Wei Hsieh, Chien‐Yu Huang   +9 more
wiley   +1 more source