Results 51 to 60 of about 1,812,803 (254)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Preoperatively Diagnosed Versus Undiagnosed Major Salivary Gland Cancer: Clinicopathological Characteristics, Treatment Strategies, and Oncological Outcomes

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate differences in clinicopathological characteristics, treatment strategies, and oncological outcomes between preoperatively diagnosed and undiagnosed major salivary gland cancers (MSGCs). Study Design Retrospective cohort study. Setting A single tertiary academic hospital. Methods Surgically confirmed MSGCs between 2012 and
Dongbin Ahn   +4 more
wiley   +1 more source

Bonneville Power Administration 1998 Annual Report.

open access: yes, 1998
This is the 1998 annual report to the President by the Administrator and Chief Executive Officer of the Bonneville Power Administration. The topics of the report include financial highlights, letter to the President, review of 1998, financial data ...
United States. Bonneville Power Administration.
core   +1 more source

Single-dose fentanyl sublingual spray for breakthrough cancer pain

open access: yesClinical Pharmacology: Advances and Applications, 2013
Donald R Taylor Comprehensive Pain Care PC, Marietta, GA, USA Abstract: Breakthrough cancer pain (BTCP) is defined as a transient exacerbation of pain that arises in patients with otherwise controlled persistent pain. BTCP typically has a rapid onset and
Taylor DR
doaj  

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco   +5 more
wiley   +1 more source

Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration

open access: yes, 2016
Tacrolimus (TCR) is an immunosuppressive drug used by oral administration. Intravenous (IV) TCR administration is required under conditions of gastrointestinal diseases or abdominal surgery at the onset of paralytic ileus.
Apicella, Luca   +21 more
core   +1 more source

Head-Up Tilt Table Testing with Sublingual Isosorbide Dinitrate in the Diagnosis of Vasovagal Syncope in Children

open access: yesEurasian Journal of Medicine, 2019
Objective: To evaluate the effect of sublingual administration of ISDN on the results of the head-up tilt table test (HUTT) in children and adolescents with vasovagal syncope. Materials and Methods: The study group consisted of 30 children, each
Mehmet Karacan, Hasim Olgun, Naci Ceviz
doaj  

A new test for diagnosing vasovagal syncope: Standing after treadmill test with sublingual nitrate administration. [PDF]

open access: yesPLoS ONE, 2017
Increased adrenergic tone might be an additional trigger of orthostatic stress of vasovagal syncope (VVS). Exercise before standing might provide increased sensitivity compared to standing using a sublingual nitroglycerines protocol during tilt table ...
Tae-Hoon Kim   +7 more
doaj   +1 more source

Craving and personal functioning as mediators of extended‐release buprenorphine efficacy: A four‐way decomposition analysis from a randomised trial

open access: yesAddiction, EarlyView.
Abstract Aims To investigate whether the treatment effect of extended‐release buprenorphine (BUP‐XR) on opioid‐free days in opioid use disorder (OUD) is mediated by reductions in opioid craving and improvements in personal functioning. Design and setting Exploratory causal mediation analysis using VanderWeele's four‐way decomposition framework in a 24 ...
John Marsden   +11 more
wiley   +1 more source

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