Results 101 to 110 of about 2,597,047 (329)

Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model

Scientific Reports
Systemic administration of Janus kinase (JAK) inhibitors is effective in treating chronic graft-versus-host disease (cGVHD) but is associated with side effects. Topical drug administration effectively minimizes side effects.
Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama   +9 more
doaj   +1 more source

NGF eye-drops topical administration in patients with retinitis pigmentosa, a pilot study

Journal of Translational Medicine, 2016
Preclinical trials have shown beneficial effects of nerve growth factor (NGF) administration on visual function in animal models of retinitis pigmentosa (RP).
B. Falsini, G. Iarossi, A. Chiaretti, A. Ruggiero, Manni Luigi, L. Galli‐Resta, G. Corbo, E. Abed   +7 more
semanticscholar   +1 more source

Screening for Social Determinants of Health in Patients With Systemic Lupus Erythematosus: A Point‐of‐Care Feasibility Study

Arthritis Care &Research, EarlyView.
Objective Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE) and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim, Vijay R. Nadipelli, Michelle Bruno, Daphne Lew, Bernard Rubin, Charmayne M. Dunlop‐Thomas, Kelsey Hulcher, Kristi R. Mitchell, Lydia Demetriou, Jeff Berko, Jason Bao, Alfred H. J. Kim   +11 more
wiley   +1 more source

Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]

, 2018
Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José, González Rodríguez, María Luisa, Motilva Sánchez, Virginia, Rabasco Álvarez, Antonio María, Rodríguez Luna, Azahara María, Talero Barrientos, Elena Mª, Ávila Román, Francisco Javier   +6 more
core   +1 more source

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

Arthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Polymer-based biomaterials for pharmaceutical and biomedical applications: a focus on topical drug administration

European Polymer Journal, 2023
P. Pires, Filipa Mascarenhas-Melo, Kelly Pedrosa, Daniel Lopes, Joana Lopes, Ana Macário‐Soares, Diana Peixoto, P. Giram, F. Veiga, Ana Cláudia Paiva-Santos   +9 more
semanticscholar   +1 more source

Nanoformulations of Rilpivirine for Topical Pericoital and Systemic Coitus-Independent Administration Efficiently Prevent HIV Transmission

PLoS Pathogens, 2015
Vaginal HIV transmission accounts for the majority of new infections worldwide. Currently, multiple efforts to prevent HIV transmission are based on pre-exposure prophylaxis with various antiretroviral drugs.
M. Kovárová, Olivia D. Council, A. Date, Julie M. Long, Tomonori Nochii, Michael Belshan, A. Shibata, Heather Vincent, Caroline E. Baker, W. Thayer, Guenter Kraus, Sophie Lachaud-Durand, P. Williams, C. Destache, J. Victor Garcia, R. Desrosiers   +15 more
semanticscholar   +1 more source

The Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Objective The aim of this systematic review was to synthesise the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye, Chidozie E.Mbada, Clara T.Fatoye, Faatihah Niyi‐Odumosu, Ushotanefe Useh, Zalmai Hakimi, Francis Fatoye   +6 more
wiley   +1 more source

Production and Characterization of Mucoadhesive Membranes for Anesthetic Vehiculation

Chemical Engineering Transactions, 2018
Studies on release systems produced from natural polymers such as chitosan (CS) have intensified in the pharmaceutical area. Polymeric membranes for the topical administration of drugs are being developed for the controlled release of drugs.
P. Severino, A.D.S. Feitosa, I.B. Isabel Bezerra Lima-Verde, M.V. Chaud, C. Da Silva, R. De Lima, R.G. Amaral, L.N. Andrade   +7 more
doaj   +1 more source

Virtual or in‐person: does it matter? Comparing pain, function, quality of life, self‐efficacy and physical function outcomes of virtual, hybrid and in‐person GLA:D Canada participants

Arthritis Care &Research, Accepted Article.
Objective This study aimed to determine if program format (in‐person, virtual, hybrid) results in differences in three‐month outcomes of pain, function, quality of life, self‐efficacy and chair stands in a hip/knee osteoarthritis management program. Methods A secondary analysis of the GLA:DTM Canada database was completed.
Jill Van Damme, Vanina Dal Bello‐Haas, Ayse Kuspinar, Patricia Strachan, Michael Zywiel, James Young, Rhona McGlasson, Lisa C. Carlesso   +7 more
wiley   +1 more source