Results 51 to 60 of about 4,786,914 (232)

Polymeric Nanoparticles as Tunable Nanocarriers for Targeted Delivery of Drugs to Skin Tissues for Treatment of Topical Skin Diseases

Pharmaceutics, 2023
The topical route is the most appropriate route for the targeted delivery of drugs to skin tissues for the treatment of local skin diseases; however, the stratum corneum (SC), the foremost layer of the skin, acts as a major barrier.
E. A. Madawi, Alaa Raad Al Jayoush, Mutasem Rawas-Qalaji, H. Thu, Shahzeb Khan, Mohammad Sohail, Asif Mahmood, Z. Hussain   +7 more
semanticscholar   +1 more source

Ice versus lidocaine 5% gel for topical anaesthesia of oral mucosa – a randomized cross-over study

BMC Anesthesiology, 2019
Background Topical anaesthesia is important to optimize pain control during dental injection. Our aim was to describe a new simple method for topical anaesthesia of oral mucosa and to compare the effectiveness of ice and lidocaine 5% gel for topical ...
Nishma Hindocha, Filip Manhem, Emmanuel Bäckryd, Mats Bågesund   +3 more
doaj   +1 more source

Comparison of topical and intravenous tranexamic acid for reducing postoperative blood loss in single-level posterior lumbar interbody fusion: a retrospective study from Japan [PDF]

Asian Spine Journal
Study Design A retrospective cohort study. Purpose This study aimed to compare the efficacy and safety of topical and relatively high-dose intravenous tranexamic acid (TXA) in minimizing postoperative blood loss in patients undergoing single-level ...
Kazuma Kitaguchi, Kunihiko Hashimoto, Takashi Kaito, Kazuya Oshima, Eiji Wada   +4 more
doaj   +1 more source

Effectiveness of topical administration of Anethum graveolens essential oil on MRSA-infected wounds.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019
Medicinal plants are conventionally used for wound healing, but their action mechanisms are still unknown. The present study evaluated the effect of topical administration of ointment containing dill (Anethum graveolens) essential oil (DEO) in the ...
Reza Manzuoerh, M. Farahpour, A. Oryan, A. Sonboli   +3 more
semanticscholar   +1 more source

Educational Administration: Theory and Practice [PDF]

, 2021
Educational Administration: Theory & Practice: Vol 25, Issue
Educational Administration Theory and Practice
core   +1 more source

The combined use of oral and topical tranexamic acid is a safe, efficient and low-cost method in reducing blood loss and transfusion rates in total knee arthroplasty

Journal of Orthopaedic Surgery, 2017
Aims: The combined (IV (intravenous) + topical) use of tranexamic acid (TXA) has been shown to be a safe method and more effective than single (IV or topical) application.
Deniz Cankaya, Uygar Dasar, Ahmet Burak Satilmis, Serdar Hakan Basaran, Mustafa Akkaya, Murat Bozkurt   +5 more
doaj   +1 more source

Improved Topical Drug Delivery: Role of Permeation Enhancers and Advanced Approaches

Pharmaceutics, 2022
The delivery of drugs via transdermal routes is an attractive approach due to ease of administration, bypassing of the first-pass metabolism, and the large skin surface area.
Victor Hmingthansanga, Nidhi Singh, Superna Banerjee, S. Manickam, Ravichandiran Velayutham, S. Natesan   +5 more
semanticscholar   +1 more source

Challenging the "Topical Medications-First” Approach to Glaucoma: A Treatment Paradigm in Evolution

Ophthalmology and Therapy, 2023
Topical glaucoma medications are effective and safe, but they have numerous well-documented limitations that diminish their long-term utility and sustainability.
N. Radcliffe, Manjool Shah, Thomas W. Samuelson   +2 more
semanticscholar   +1 more source

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

Pharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang, Hongmei Hu, Qian Jing, Zhi Wang, Zehui He, Tong Wu, Nian-Ping Feng   +6 more
doaj   +1 more source

Topical versus intravenous administration of tranexamic acid in primary total hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials

Orthopedic Reviews, 2016
Tranexamic acid (TA) is widely used by orthopedic surgeons to decrease blood loss and the need for transfusion following total hip arthroplasty (THA). Although both intravenous and topical applications are described in the literature, there remains no ...
Sammy A. Hanna, Anoop Prasad, Joshua Lee, Pramod Achan   +3 more
doaj   +1 more source