Results 41 to 50 of about 134,727 (261)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Administrative reforms in South Eastern European states. Comparative study in view of enlarging the European Administrative Space. 2010 Sino-US International Conference on Public Administration (5th), June 14-17, 2010, Xiamen City, P.R. China [PDF]

open access: yes, 2010
The accession and enlargement of the European integration process have determined, especially in the last decade, profound reforms aimed at changing the national public administrations in consensus with the developments of the administrations in the ...
Matei, Lucica, Matei, Ani
core  

SECOND INSTANCE ADMINISTRATIVE COMMISSIONS AND THE ADMINISTRATIVE COURTS EFFICIENCY IN THE REPUBLIC OF NORTH MACEDONIA

open access: yes, 2020
The paper aims to evaluate the direct and indirect determinants of the system for administrative legal protection efficiency in the Republic of North Macedonia.
Akimovska Maletic, Iskra   +2 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Simplification of Administrative Procedures through Fully Automated Decision-Making: The Case of Norway [PDF]

open access: yes, 2021
Norway has a high degree of digitalisation. In the public sector, there is a long tradition of automation of parts of case management. This includes automation of cases where a public sector body makes a so-called individual administrative decision, that
Weitzenboeck, Emily Mary   +2 more
core   +1 more source

The Impact of Contractual Governance on Project Performance in Urban Sewage Treatment Public–Private Partnership Projects: The Moderating Role of Administrative Efficiency

open access: yesBuildings
In public–private partnership (PPP) projects, the private sector’s performance is influenced by administrative efficiency, and the impact varies across different contractual dimensions.
Jialin Gui, Jinbo Song, Wen Xia
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

MARKETING EFFICIENCY OF TOMATO CROP IN SHARKIA GOVERNORATE [PDF]

open access: yesJournal of Productivity and Development, 2019
The research aims at measuring the marketing efficiency of the winter tomato crop in Sharkia Governorate by estimating the economic and administrative indicators of the crop market, calculating the marketing margins, distributing the consumer pounds and ...
shimaa Abosena   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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