Results 61 to 70 of about 134,727 (261)
Central European Public Administration Review, 2019 The aim of this article is to evaluate the effectiveness and efficiency of (internal) administrative appeal in tax or fiscal matters in Romania, in comparison to the more time and resource consuming court action against an administrative decision ...
Octavian Moldovan, Gabriela Bucătariu
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Reconciling Administrative Efficiency with Procedural Safeguards in the ADM System
Bratislava Law ReviewThe use of automated systems for making administrative decisions has recently increased to improve efficiency and speed in completing tasks. However, ensuring that administrative effectiveness aligns with procedural safeguards when using an Automated ...
Eltayeib Sharaf Addin
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Administrative Costs and Production Efficiency. [PDF]
Economists providing policy advice often justify recommendations of government non-interference in the allocation of resources between production sectors and free trade with reference to the Diamond and Mirrlees efficiency theorem.
K.J.MUNK
core
, 2015 Upravna doktrina je logički usklađen skup ideja o poželjnim vrijednim načinima organiziranja i djelovanje javne uprave. Upravna doktrina nije teorija i nema znanstvene ambicije.
Petković, Andrea
core
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
THE ACTIVATION OF THE PRINCIPLES OF GOVERNMENT AT THREE ADMINISTRATIVE LEVELS [PDF]
Annals of the University of Craiova: Economic Sciences Series, 2017 The present article aims to identify at three administrative levels- the level subordinated to the local administrative level, the local administrative level and the county administrative level -what are the principles of governance under which ...
Dorina Țicu
doaj
ADMINISTRATIVE CONVERGENCE AND REFORMS IN SOUTH-EASTERN EUROPEAN STATES - Analyses, models and comparative studies [PDF]
The fundamental idea of the current publication emphasizes the characteristics of the processes related to administrative convergence and reform in the South-Eastern European states. Of course the area under review is quite wide and complex and therefore
Ani Matei, Panagiotis Grigoriou
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source