Results 61 to 70 of about 4,250,233 (251)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

THE ROLE OF SALES ADMIN IN SUPPORTING ADMINISTRATIVE EFFICIENCY FOR SALES MARKETING DEPARTMENT PERFORMANCE AT NOVOTEL SEMARANG

open access: yesJournal of Management Small and Medium Enterprises (SME's)
This study examines the role of Sales Admin in supporting administrative efficiency for Sales Marketing Department performance at Novotel Semarang.
Adinda Consita Yulianne Prabowo   +1 more
doaj   +1 more source

Utah Administrative Code 1989, Volume 3

open access: yes, 1989
Series 83623 | Utah Division of Administrative Rules | Utah Administrative Code | Utah Administrative Code 1989, Volume 3The Utah Administrative Code is the authorized compilation of the administrative law of Utah (See Utah Code Section 63-46a-16 (1987 ...
Utah Division of Administrative Rules
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Reconciling Administrative Efficiency with Procedural Safeguards in the ADM System

open access: yesBratislava Law Review
The use of automated systems for making administrative decisions has recently increased to improve efficiency and speed in completing tasks. However, ensuring that administrative effectiveness aligns with procedural safeguards when using an Automated ...
Eltayeib Sharaf Addin
doaj   +1 more source

Utah Administrative Code 1987-1988, Volume 1

open access: yes, 1987
Series 83623 | Utah Division of Administrative Rules | Utah Administrative Code | Utah Administrative Code 1987-1988, Volume 1The Utah Administrative Code is the authorized compilation of the administrative law of Utah (See Utah Code Section 63-46a-16 ...
Utah Division of Administrative Rules
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Effectiveness and Efficiency of Administrative Appeal Procedures: a Case Study on Tax Disputes in Romania

open access: yesCentral European Public Administration Review, 2019
The aim of this article is to evaluate the effectiveness and efficiency of (internal) administrative appeal in tax or fiscal matters in Romania, in comparison to the more time and resource consuming court action against an administrative decision ...
Octavian Moldovan, Gabriela Bucătariu
doaj   +1 more source

Utah Administrative Code 1987-1988, Volume 3

open access: yes, 1987
Series 83623 | Utah Division of Administrative Rules | Utah Administrative Code | Utah Administrative Code 1987-1988, Volume 3The Utah Administrative Code is the authorized compilation of the administrative law of Utah (See Utah Code Section 63-46a-16 ...
Utah Division of Administrative Rules
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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