Results 51 to 60 of about 4,250,233 (251)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Report of the Energy Efficiency Board. 2013.
, 2014 Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core +1 more source
Journal of Innovation & KnowledgeAdministrative pressure on local officials concerning environmental performance is a pivotal factor influencing regional green development. To explore how such pressure affects green innovation efficiency—a key determinant of competitive sustainability ...
Guoliang Jiang, Fang Zhao, Xing Liu
doaj +1 more source
Efficiency and inefficiency of public administration [PDF]
Journal of Economic Development, Environment and People, 2018 Public administration and local government in particular, which also includes municipalities in individual countries, is in the context of the economic crisis a very topical and widely discussed issue. The management of municipalities is subject to increasing control by the public, the state and the municipalities themselves.
openaire +2 more sources
Department of Administrative Services (DAS) program on resident bidders under Public Act 11-229
, 2012 "Pursuant to the provisions of section 9 of Public Act 11-229, the Department of Administrative Services (DAS) in consultation with the Commissioner of Labor, the President of the University of Connecticut, the Commissioner of Public Works (now the ...
Connecticut. Dept. of Administrative Services.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Utah Administrative Code 1989, Volume 4
, 1987 Series 83623 | Utah Division of Administrative Rules | Utah Administrative Code | Utah Administrative Code 1989, Volume 4The Utah Administrative Code is the authorized compilation of the administrative law of Utah (See Utah Code Section 63-46a-16 (1987 ...
Utah Division of Administrative Rules
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Discussion on the Relationship of Administrative Efficiency and Administrative Efficacy
Advances in Intelligent Systems Research, 2014 In the administration field, the concepts of administrative efficiency and administrative efficacy are closely related but easy to be confused. Generally, administrative efficacy can direct administrative efficiency and contrarily be reflected by administrative efficiency. At the same time, there are some fundamental differences between them, including
openaire +2 more sources
Utah Administrative Code 1987-1988, Volume 2
, 1987 Series 83623 | Utah Division of Administrative Rules | Utah Administrative Code | Utah Administrative Code 1987-1988, Volume 2The Utah Administrative Code is the authorized compilation of the administrative law of Utah (See Utah Code Section 63-46a-16 ...
Utah Division of Administrative Rules
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