Results 1 to 10 of about 2,066 (126)
Cells, 2022 (1) Background: Activity-dependent neuroprotective protein (ADNP) is essential for neuronal structure and function. Multiple de novo pathological mutations in ADNP cause the autistic ADNP syndrome, and they have been further suggested to affect Alzheimer’
Gidon Karmon +2 more
exaly +3 more sources
Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting
Cells, 2020 Activity-dependent neuroprotective protein (ADNP) mutations are linked with cognitive dysfunctions characterizing the autistic-like ADNP syndrome patients, who also suffer from delayed motor maturation.
Meishar Shahoha +2 more
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The ADNP Syndrome and CP201 (NAP) Potential and Hope
Frontiers in Neurology, 2020 Activity-dependent neuroprotective protein (ADNP) syndrome, also known as Helsmoortel-Van Der Aa syndrome, is a rare condition, which is diagnosed in children exhibiting signs of autism.
Illana Gozes
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ADNP Syndrome: A Qualitative Assessment of Symptoms, Therapies, and Challenges
Children, 2023 ADNP syndrome is a neurodevelopmental disorder characterized by autism spectrum disorder (ASD), intellectual disability, sensory reactivity symptoms, facial dysmorphisms, and a wide variety of other physical and behavioral health manifestations. Research
Alexander Kolevzon, Jarrett Fastman
exaly +3 more sources
Cells, 2023 (1) Background: Recently, we showed aberrant nuclear/cytoplasmic boundaries/activity-dependent neuroprotective protein (ADNP) distribution in ADNP-mutated cells.
Gidon Karmon +2 more
exaly +3 more sources
Human Genetics and Genomics Advances, 2022 Summary: Activity-dependent neuroprotective protein (ADNP) syndrome is a rare genetic condition associated with intellectual disability and autism spectrum disorder.
Alexander Kolevzon +2 more
exaly +3 more sources
BMC Medical Genomics, 2023 Background Hepatocellular carcinoma (HCC) is one of the most lethal diseases due to its high faculty of invasiveness and metastasis. Activity-dependent neuroprotective protein (ADNP) has been regarded as an oncogene in bladder cancer and ovarian cancer ...
Xuan Wang +6 more
doaj +1 more source
ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4
Frontiers in Cell and Developmental Biology, 2020 ADNP (Activity Dependent Neuroprotective Protein) is proposed as a neuroprotective protein whose aberrant expression has been frequently linked to rare neural developmental disorders and cancers, including the recently described neurodevelopmental ...
XiaoYun Sun +4 more
doaj +1 more source
Pharmaceutics, 2020 The aim of this study is to prepare and characterize an amino-dextran nanoparticle (aDNP) platform and investigate two loading strategies for unmethylated cytosine-phosphate-guanine (CpG) oligonucleotide. aDNP was prepared by desolvation of amino-dextran
Hien V. Nguyen +4 more
doaj +1 more source
ADNP Upregulation Promotes Bladder Cancer Cell Proliferation via the AKT Pathway
Frontiers in Oncology, 2020 BackgroundActivity-dependent neuroprotective protein (ADNP), which is involved in embryonic development and neurogenesis, has been proven to be upregulated in some human tumors.
Shuai Zhu +10 more
doaj +1 more source