Results 91 to 100 of about 377,496 (294)

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions

Frontiers in Immunology, 2019
Adoptive cell transfer therapy is currently one of the most promising approaches for cancer treatment. This therapy has some limitations, however, such as the dispersion of in vivo-administered cells, causing only a small proportion to reach the tumor ...
L. Sanz-Ortega, J. Rojas, Yadileiny Portilla, S. Pérez-Yagüe, D. F. Barber   +4 more
semanticscholar   +1 more source

Adoptive cell transfer of macrophages following peripheral nerve injury in mice. [PDF]

STAR Protoc, 2023
Rawat A, Jha MK, Morrison BM.
europepmc   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Adoptive cell transfer immunotherapy for patients with solid epithelial cancers. [PDF]

Cancer Cell, 2023
Rosenberg SA, Parkhurst MR, Robbins PF.
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Doxorubicin eliminates myeloid-derived suppressor cells and enhances the efficacy of adoptive T-cell transfer in breast cancer.

Cancer Research, 2014
Myeloid-derived suppressor cells (MDSC) expand in tumor-bearing hosts and play a central role in cancer immune evasion by inhibiting adaptive and innate immunity. They therefore represent a major obstacle for successful cancer immunotherapy.
D. Alizadeh, Malika Trad, Neale T. Hanke, C. Larmonier, N. Janikashvili, B. Bonnotte, Emmanuel Katsanis, N. Larmonier   +7 more
semanticscholar   +1 more source

Local Irradiation Sensitized Tumors to Adoptive T Cell Therapy via Enhancing the Cross-Priming, Homing, and Cytotoxicity of Antigen-Specific CD8 T Cells

Frontiers in Immunology, 2019
The successful generation of T cell-mediated immunity for the treatment of cancer has been a major focal point of research. One of the critical strategies of cancer immunotherapy is to efficiently activate antigen-specific CD8 T cells in the ...
Jin-Zhi Lai, Jin-Zhi Lai, Yan-Yang Zhu, Mei Ruan, Ling Chen, Qiu-Yu Zhang   +5 more
doaj   +1 more source

Development of a Novel Processing Route for Dispersoid/Precipitation‐Strengthened High Conductive Copper Alloys by Using Metalized Nanoceramics in Additive Manufacturing

Advanced Engineering Materials, EarlyView.
This study explores a process chain to produce dispersoid‐strengthened CuCr1Zr for applications requiring high strength and conductivity. Using gas‐atomized powder and copper‐plated alumina nanoparticles, additive manufacturing is performed via powder bed based additive manufacturing with green and red lasers, followed by heat treatment.
Heinrich von Lintel, Abdelrahman Elsayed, Lukas Mielewczyk, Katja Eichmann, Julia Grothe, Ulrich Krupp, Avinash Hariharan, Katrin Jahns   +7 more
wiley   +1 more source

Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy.

Cancer Discovery, 2013
UNLABELLED Adoptive cell transfer (ACT) of genetically engineered T cells expressing cancer-specific T-cell receptors (TCR) is a promising cancer treatment.
Chao Ma, Ann F. Cheung, T. Chodon, R. Koya, Zhongqi-Phyllis Wu, Charles Ng, Earl V Avramis, A. Cochran, O. Witte, D. Baltimore, B. Chmielowski, J. Economou, Begonya Comin-Anduix, A. Ribas, J. Heath   +14 more
semanticscholar   +1 more source